ReviewFrontiers in medicine2025
The pathogenesis, risk factors, diagnosis and treatment of Acanthamoeba keratitis.
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Implication of Horizontal Gene Transfer BetweenPathogens (Basel, Switzerland) · 2026Pooled it
- Oxidative Stress and Redox Imbalance inInternational journal of molecular sciences · 2026Review
- Microenvironment-Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges.Small science · 2026Review
- Host Response and Pathogen Load in Acanthamoeba Keratitis: A Histopathological Analysis.Investigative ophthalmology & visual science · 2026Article
- Article
- Acanthamoeba keratitis: from pathophysiology to prevention, a contemporary clinical perspective.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Review
- Case Report: Confocal microscopy in the early diagnosis of microsporidial keratitis.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acanthamoeba keratitis (AK) is a rare corneal disease that can lead to permanent visual impairment. Its incidence is relatively low when compared with that of other forms of infectious keratitis. As early clinical diagnosis of AK is challenging (e.g., overlapping symptoms, lack of specific diagnostic tools, etc.), it is often misdiagnosed as other types of infectious keratitis, such as viral keratitis or fungal keratitis. Once a patient is diagnosed with AK, the prognosis is extremely poor unless an early start of an aggressive treatment program is implemented, as timely diagnosis and treatment are closely related to a good prognosis. AK can be diagnosed through corneal scraping, culture, polymerase chain reaction, or
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.