Evidence map›Paper›PMID 40777654›Full record

ArticleFrontiers in public health2025

A capacity strengthening model toward self-reliant and sustainable one-health workforce in six East African Community Partner States.

Julien A Nguinkal, Florian Gehre, Hakim I Lagu, Emmanuel Achol, Eric Nzeyimana, John N Kiiru, Joseph Nyandwi, Gregory W Dumo, Nyambura Moremi, Susan N Nabadda and 4 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Julien A NguinkalDepartment of Infectious Disease Epidemiology, Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany.
Florian GehreDepartment of Infectious Disease Epidemiology, Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany.
Hakim I LaguHealth Department, East African Community (EAC), Arusha, Tanzania.
Emmanuel AcholHealth Department, East African Community (EAC), Arusha, Tanzania.
Eric NzeyimanaHealth Department, East African Community (EAC), Arusha, Tanzania.
John N KiiruDepartment of Disease Surveillance and Epidemic Response, Ministry of Health, Nairobi, Kenya.
Joseph NyandwiNational Reference Laboratory, National Institute of Public Health, Bujumbura, Burundi.
Gregory W DumoNational Public Health Laboratory, Ministry of Health, Juba, South Sudan.
Nyambura MoremiNational Public Health Laboratory, Ministry of Health, Dar es Salaam, Tanzania.
Susan N NabaddaCentral Public Health Laboratories, National Health Laboratories, Ministry of Health, Kampala, Uganda.
Isabelle MukagatareBiomedical Services Department, Rwanda Biomedical Centre, Kigali, Rwanda.
Andrea MolinaDepartment of Infectious Disease Epidemiology, Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany.
Jürgen MayDepartment of Infectious Disease Epidemiology, Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany.
Muna AffaraDepartment of Infectious Disease Epidemiology, Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The burden of infectious diseases and antimicrobial resistance (AMR) in Africa highlights the critical need for strengthened genomic surveillance capacities that are embedded within the national public health framework. In the East African Community (EAC), this challenge is compounded by limited infrastructure and insufficient workforce capacity in bioinformatics and genomics, particularly within National Public Health Laboratories (NPHLs). This paper describes the implementation of a regional capacity-building initiative based on a multi-phase Training-of-Trainers (ToT) model across six EAC Partner States. Anchored in a One Health framework, the initiative focused on equipping public health professionals within NPHLs with practical skills in pathogen genomics, AMR analysis, and bioinformatics workflows, while also supporting the institutionalization of standardized procedures and tools. Through modular training, in-country cascade sessions, and structured mentorship, the program enabled integration of genomic approaches into public health surveillance activities. Despite infrastructural and operational constraints, the initiative supported measurable gains in applied proficiency, routine use of genomics tools in surveillance tasks, and regional coordination on pathogen data analysis. This case study outlines the program's design, implementation, and observed outcomes, and offers a transferable framework for workforce and systems development in low-resource settings. This experience contributes to ongoing global discussions on equitable genomic surveillance and preparedness by demonstrating how structured, context-specific training can support sustainable adoption of genomics within national public health institutions.

Indexed as

Capacity BuildingOne HealthPublic HealthAfrica, EasternComputational BiologyEast African PeopleGenomicsHumansantimicrobial resistance (AMR)bioinformatics capacity buildingEast African Community (EAC)genomic surveillanceNational Public Health Laboratories (NPHLs)One HealthTraining-of-Trainers (ToT)

Identifiers

PMID40777654
PMCPMC12328454

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.