Evidence map›Paper›PMID 40778166›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Altered oscillatory coupling reflects possible inhibitory interneuron dysfunction in Rett syndrome.

Devorah Kranz, Yael Braverman, Michelle McCarthy, Claire Mackay, Karen N Sabol, Tim A Benke, David N Lieberman, Eric D Marsh, Jeffrey L Neul, Fleming Peck and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Devorah KranzBoston Children's Hospital, Boston, MA 02115.ORCID 0000-0002-8821-8885
Yael BravermanBoston Children's Hospital, Boston, MA 02115.
Michelle McCarthyInternational Research Center for Neurointelligence, University of Tokyo, Tokyo, Japan.
Claire MackayBoston Children's Hospital, Boston, MA 02115.
Karen N SabolBoston Children's Hospital, Boston, MA 02115.
Tim A BenkeDepartments of Pediatrics, Pharmacology, Neurology and Otolaryngology, University of Colorado School of Medicine.
David N LiebermanBoston Children's Hospital, Boston, MA 02115.
Eric D MarshDepartments of Neurology and Pediatrics, University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia PA 19096.
Jeffrey L NeulDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville TN 37203.
Fleming PeckDepartment of Psychology, University of California, Los Angeles, Los Angeles CA 90095.
Alan K PercyDepartment of Pediatrics (Neurology), University of Alabama at Birmingham, Birmingham AL.
Joni SabyDepartments of Neurology and Pediatrics, University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia PA 19096.
Nancy KopellInternational Research Center for Neurointelligence, University of Tokyo, Tokyo, Japan.
Charles A NelsonBoston Children's Hospital, Boston, MA 02115.
April R LevinBoston Children's Hospital, Boston, MA 02115.ORCID 0000-0003-4192-4720
Michela FagioliniBoston Children's Hospital, Boston, MA 02115.

Funding

Training and Career Development ComponentU54HD061222 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PERCY, ALAN KENNETH · 2009 to 2019
$12.4M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
NICHD NIH HHS P50 HD103537NICHD NIH HHS P50 HD105351NICHD NIH HHS U54 HD061222
6 · The paper itself

Abstract

Rett syndrome is a rare neurodevelopmental disorder caused primarily by pathogenic variants in the

Indexed as

EEGneurogenetic disordersphase-amplitude couplingRett syndromeVIP+ interneurons

Identifiers

PMID40778166
PMCPMC12330464

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.