ArticleFrontiers in pain research (Lausanne, Switzerland)2025
Whole-body cryostimulation exposures effectively alleviates menstrual-related pain and associated sleep disturbances in young women: a randomized controlled trial.
Article in Frontiers in pain research (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Menstrual-related pain and sleep disturbances are widespread in women experiencing premenstrual syndrome and primary dysmenorrhea. Such disturbances could be alleviated through repeated whole-body cryostimulation (WBC) sessions. Therefore, this study aimed to assess the effect of menstrual-related pain on sleep parameters, and the impact of WBC exposures on pain and sleep. Materials and methods: Pain and sleep were evaluated for two 5-day periods under different conditions (control vs. WBC), randomly assigned across two consecutive menstrual cycles. Measurements began when the first pain/symptom indicating the onset of the menstrual phase was experienced. Pain was rated using a scale, while sleep was assessed using accelerometers and questionnaires. Throughout the 5-day WBC exposure, women underwent 3-min exposure to intense ventilated cold air each evening. After data collection, participants were categorized into high (HP) or low/no pain (LP) groups based on control pain scores. Results: Twenty-nine naturally menstruating women were assessed. Perceived sleep quality was lower in the HP group compared to the LP group during the control condition (Spiegel score: 20.1 ± 2.3 vs. 22.3 ± 1.9, respectively; Cohen's Discussion: Women experiencing higher menstrual-related pain reported poorer perceived sleep quality. Their pain was reduced by WBC exposures. This improvement was highly associated with the enhancement in sleep quality.
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