Evidence mapPaperPMID 40779000Full record

Trial reportSleep & breathing = Schlaf & Atmung2025

Osa in women: When does cpap increase blood pressure?

Grace Oscullo, Amina Bekki, Thais Beaperthuy, Jose Daniel Gómez-Olivas, Marina Anglés, Sergio Mompeán, Rosalía Martínez, Silvia Ponce, Martino F Pengo, Miguel Angel Martinez-Garcia

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grace OsculloRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Amina BekkiRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Thais BeaperthuyRespiratory Unit, Requena General Hospital, Valencia, Spain.
Jose Daniel Gómez-OlivasRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Marina AnglésRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Sergio MompeánRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Rosalía MartínezRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Silvia PonceRespiratory Department, Hospital Peset Aleixandre. Valencia, Valencia, Spain.
Martino F PengoDepartment of Cardiovascular, Neural and Metabolic Sciences, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Miguel Angel Martinez-GarciaRespiratory Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain. mianmartinezgarcia@gmail.com.ORCID 0000-0002-7321-1891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been only one randomised clinical trial (RCT) on the effect of CPAP on women at three months. It showed that, overall, this treatment had no effect on blood pressure levels, even though some of the women presented increased blood pressure while under CPAP. Identifying this group of women could therefore be of clinical interest.

objectiveTo identify the risk factors for an increase (of at least 2 mmHg of BP) by analysing the CPAP arm of this RCT in those patients with inadequate and good adherence to CPAP.

methods151 women from the CPAP arm of the RCT were included. They all followed a complete sleep protocol that included CPAP pressure titration and office BP measures at baseline and one and three months after beginning CPAP treatment.

resultsAfter exclusion, 137 women began the study. 69.3% showed good adherence to CPAP at 3 months and 77 patients (56.2%) increased their BP. In the overall group of women (independently of their adherence to CPAP), age, the presence of depression, baseline AHI and baseline SBP were associated with an increased BP (at least 2 mmHg) at 1 and 3 months. However, the BP increase was observed during the first month and tended to stabilize towards the third month.

conclusionGreater age, the presence of depression and higher baseline AHI and SBP were independently associated with a clinical significant increase in BP after CPAP, regardless of their adherence. These changes in BP appeared mainly during the first month of treatment.

Indexed as

Blood PressureContinuous Positive Airway PressureHypertensionSleep Apnea, ObstructiveAdultAgedFemaleHumansMiddle AgedPatient ComplianceRisk FactorsHypersomniaHypertensionObstructive sleep apnea; CPAPWomen

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.