Evidence map›Paper›PMID 40779156›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Enhancing skin residence time of penciclovir for the treatment of cold sores: formulation and characterization of controlled release microsponges.

Rajesh Devani, Sohil Chauhan, Kiran Dudhat

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rajesh DevaniSchool of Pharmacy, RK University, Rajkot, 360020, Gujarat, India.
Sohil ChauhanSchool of Pharmacy, RK University, Rajkot, 360020, Gujarat, India.
Kiran DudhatSchool of Pharmacy, RK University, Rajkot, 360020, Gujarat, India. kiran.dudhat@rku.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to enhance the residence time of penciclovir on the skin by developing controlled-release microsponges to improve therapeutic efficacy for the treatment of cold sores. Microsponges were prepared using the quasi-emulsion solvent diffusion method. Ethyl cellulose was selected as the internal phase polymer, and dichloromethane was chosen as the solvent based on preliminary studies. A 3

Indexed as

AcyclovirAntiviral AgentsSkinAdministration, CutaneousAnimalsCelluloseChemistry, PharmaceuticalDelayed-Action PreparationsDrug CompoundingDrug LiberationDrug StabilityGuanineParticle SizeSkin AbsorptionAcyclovirAntiviral AgentsCelluloseDelayed-Action Preparationsethyl celluloseGuaninepenciclovir32 full factorial designCold soresMicrospongePenciclovirQuasi emulsion solvent diffusion

Identifiers

PMID40779156

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.