Evidence mapPaperPMID 40779228Full record

ArticleInsights into imaging2025

Positivity rates and subsequent patient dispositions after utilisation of cervical spine imaging referral guidelines in Singapore.

Yi Xiang Tay, Shane J Foley, Ronan Killeen, Marcus E H Ong, Robert Chun Chen, Lai Peng Chan, Eu Jin Tan, May San Mak, Wenlu Hou, Jonathan P McNulty

Abstract read
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yi Xiang TayRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland. yi.tay@ucdconnect.ie.ORCID http://orcid.org/0000-0001-8322-1500
Shane J FoleyRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.
Ronan KilleenSt Vincent's University Hospital, Dublin, Ireland.
Marcus E H OngDepartment of Emergency Medicine, Division of Medicine, Singapore General Hospital, Singapore, Singapore.
Robert Chun ChenDuke-NUS Graduate Medical School, Singapore, Singapore.
Lai Peng ChanDuke-NUS Graduate Medical School, Singapore, Singapore.
Eu Jin TanDuke-NUS Graduate Medical School, Singapore, Singapore.
May San MakDuke-NUS Graduate Medical School, Singapore, Singapore.
Wenlu HouDuke-NUS Graduate Medical School, Singapore, Singapore.
Jonathan P McNultyRadiography and Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.

Funding

Singapore General Hospital N/ASingHealth N/A
6 · The paper itself

Abstract

objectivesThis study seeks to evaluate the imaging characteristics and patient outcomes from the imaging recommendations of the ACR Appropriateness Criteria (AC), the ESR iGuide, and RCR iRefer. MATERIALS AND

methodsThis retrospective study evaluated cervical spine X-rays and CTs performed consecutively in a Singapore emergency department (ED) between October 1st and December 31st, 2022. Patient demographics, clinical diagnosis, ED clinical notes, and radiological findings were extracted from the electronic health record and subsequently reviewed to determine the associated imaging recommendations.

results452 (mean age, 56 ± 17.3 years, 54.9% female) and 153 (mean age, 52.8 ± 21.4 years, 65.4% male) patients underwent X-ray and CT cervical spine, respectively. According to ACR AC and ESR iGuide, the positivity rate (4.3-7.2%) was the highest for appropriate studies and the lowest (0%) for inappropriate studies. For RCR iRefer, positivity rates (1.1-7.0%) were only observed for imaging classified as "Indicated only in specific circumstances". There was a minimal difference in the proportion of patients with radiological findings that were categorised as positive and negative across the recommendations from the three guidelines. Most patients with inappropriate imaging in the X-ray cohort were discharged home or referred to specialists, whereas those in the CT cohort were primarily admitted to the hospital for conditions unrelated to the cervical spine.

conclusionsInappropriate cervical spine imaging was associated with a lack of positive, significant findings. Imaging referral guidelines are specific and can effectively rule out significant pathology when imaging in the ED is not indicated. Clinical practice in the ED must incorporate imaging referral guidelines. CRITICAL RELEVANCE STATEMENT: Imaging referral guidelines were effective in excluding a positive finding in traumatic and non-traumatic patients, especially when aligned with evidence-based clinical criteria. KEY POINTS: There are numerous imaging referral guidelines with unique methodologies, but the impact of individual imaging recommendations on imaging characteristics and patient dispositions remains unclear. There is minimal difference in the positivity rates across individual imaging recommendations from all three imaging referral guidelines. Inappropriate cervical spine imaging was associated with a lack of positive, significant findings. Guidelines are still effective in excluding significant pathology when imaging is not indicated.

Indexed as

Clinical decision-makingDiagnostic imagingEvidence-based practiceRadiologyValue-based health care

Identifiers

PMID40779228
PMCPMC12334777

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.