Trial reportBMC anesthesiology2025
Effects of combining epidural with general anesthesia on postoperative sleep and pain in elderly patients undergoing gastrointestinal tumor surgery: a prospective randomized trial.
Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- The impact of intrathecal analgesia with diamorphine on postoperative recovery in elective robotic-assisted colorectal surgery: a retrospective cohort study.Journal of robotic surgery · 2025Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative sleep disturbance is one of the most important factors affecting rapid postoperative recovery. The aim of the present study was to investigate the effects of combined epidural and general anesthesia on postoperative sleep and pain in elderly patients undergoing gastrointestinal tumor surgery. PATIENTS AND
methodsNinety patients who were scheduled to undergo elective gastrointestinal tumor surgery were randomly divided into the general anesthesia (GA) and epidural combined with GA (GEA) groups. A wireless smart bracelet was used to measure objective sleep quality on the night before surgery (Preop 1), and on the first, third, and seventh night after surgery (POD1, POD3, and POD7, respectively). Subjective sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI) scale. Furthermore, the total dose of general anesthetics required and postoperative pain and adverse effects were assessed.
resultsPSQI was higher on postoperative day 1 and day 3 than on preoperative day 1 in both groups. In addition, on postoperative day 1 and postoperative day 3, PSQI scores were lower in the GEA group than in the GA group. On postoperative day 1, the sleep scores, rapid eye movement sleep, and percentage of stable sleep were higher in the GEA group than in the GA group. remifentanil dosage and the incidence of postoperative nausea and vomiting were significantly lower in the GEA group than in the GA group. There was no significant difference in VAS scores at 6, 24, 48 h after operation and total PCA demand attempts within 48 h after operation between the two groups.
conclusionElderly patients usually experience considerable sleep disturbances after gastrointestinal tumor surgery. Epidural combined with GA can effectively improve postoperative short-term sleep quality and reduce the incidence of postoperative nausea and vomiting. This may be related to the reduction of intraoperative consumption of remifentanil under epidural anesthesia. However, the pain within 48 h after the operation was not improved in this study.
trial registrationThe study was registered at Chinese Clinical Trial Registry http//www.chictr.org.cn/ (Registration date 04/04/2021 Trial ID ChiCTR2100045064).
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