ArticleJapanese journal of radiology2025
Assessment of perivascular adipose tissue attenuation using dual-layer spectral-detector CTA for identification of symptomatic carotid plaques.
Article in Japanese journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Spectral CT parameters of perivascular adipose tissue as non-invasive biomarkers for identifying symptomatic carotid atherosclerosis.Insights into imaging · 2026Article
- Plaque-Level Machine Learning Prediction of Intraplaque Hemorrhage in Carotid Arteries Using Computed Tomography Angiography.Clinical neuroradiology · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
purposeTo assess the attenuation of perivascular adipose tissue (PVAT) around carotid plaques on Dual-layer spectral-detector dual-energy computed tomography angiography (DLCTA) and explore its application values for the identification of symptomatic carotid plaques. MATERIALS AND
methodsPatients with carotid plaques were enrolled and underwent DLCTA. The PVAT surrounding carotid plaques was outlined and the attenuation was measured on virtual monoenergetic images (40 keV and 70 keV) and polyenergetic imaging (PI). The PVAT attenuation was compared between symptomatic and asymptomatic plaques. The diagnostic performances of PVAT attenuation in differentiating symptomatic plaques were analyzed using receiver operating characteristic (ROC) curves.
resultsA total of 73 patients (65.3 ± 7.9 years, 61 males) were included (symptomatic group, n = 29; asymptomatic group, n = 44). On monoenergetic 40 keV, 70 keV, and PI, PVAT attenuation was found significantly higher in the symptomatic plaques compared to the asymptomatic plaques (P < 0.001, P < 0.001, and P = 0.002 respectively). The area under the curves (AUCs) of PVAT
conclusionsDLCTA-derived PVAT attenuation might serve as a good imaging marker of symptomatic carotid plaques. Including PVAT attenuation on 40 keV images in clinical assessment, may help improve the abilities in the detection and identification of symptomatic carotid plaques.
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Registered trials
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