Evidence map›Paper›PMID 40783650›Full record

ArticleCommunications biology2025

Multi-omics insights of immune cells in the risk and prognosis of idiopathic membranous nephropathy.

Xiaoyi Song, Wen Zhu, Yang Li, Zhanyu Li, Wanwei Cao, Jieyu Lu, Wanping Pan, Jingyue Wei, Man Li

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoyi Song *Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Wen Zhu *Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Yang Li *Department of Cardiothoracic Surgery, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Zhanyu LiDepartment of Pathology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Wanwei CaoDepartment of Pathology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Jieyu LuGuangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Wanping PanGuangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Jingyue WeiGuangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China.
Man LiGuangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, China. liman26@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-3839-0281

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82000628
6 · The paper itself

Abstract

Idiopathic membranous nephropathy (IMN) is the major cause of autoimmune-related nephrotic syndrome. The role immune cells play in the risk and prognosis of IMN remains elusive. We employ multi-omics data and a variety of approaches to evaluate the causal link between 731 immune-cell phenotypes and IMN. In light of the findings emanating from Mendelian randomization analyses, only the regulatory T cell (Treg) subtype (CD39

Indexed as

Glomerulonephritis, MembranousT-Lymphocytes, RegulatoryAntigens, CDApyraseFemaleGene Expression ProfilingHumansMaleMiddle AgedMultiomicsPrognosisRisk FactorsTranscriptomeAntigens, CDApyrase

Identifiers

PMID40783650
PMCPMC12335521

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.