Evidence map›Paper›PMID 40783689›Full record

ArticleBMC geriatrics2025

Efficacy of progressive resistance training intensities and adequate dietary protein intake for community-dwelling frail older adults (TEAMS study), protocol for a randomised controlled trial.

M Benali, J van den Helder, E J M Biersteker, J D Schoufour, P J M Weijs, M Tieland

Abstract readClinical Trial Protocol
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Human whole-blood NADNature metabolism · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M BenaliFaculty of Health, Sport and Physical Activity, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands. m.benali@hva.nl.
J van den HelderFaculty of Health, Sport and Physical Activity, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
E J M BierstekerFaculty of Health, Sport and Physical Activity, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
J D SchoufourFaculty of Health, Sport and Physical Activity, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
P J M WeijsFaculty of Health, Sport and Physical Activity, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
M TielandFaculty of Health, Sport and Physical Activity, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.

Funding

Taskforce for Applied Research SIA (part of the Dutch Research Council NWO) RAAK.PRO03.062
6 · The paper itself

Abstract

backgroundProgressive Resistance Training (PRT) and adequate dietary protein are crucial for preventing and managing sarcopenia and frailty in older adults. To date, the optimal intensity of PRT and the added value of dietary protein for enhancing muscle mass, strength, and physical performance in frail older adults remain unclear. This randomised controlled trial aims to determine the efficacy of various PRT intensities and adequate dietary protein intake in improving muscle mass, strength and physical performance in frail, community-dwelling older adults.

methodsThis study is a two-step randomised clinical trial involving 300 frail older adults. Participants will engage in a 12-week PRT twice weekly. Initially, participants will be randomised to specific training intensities, ranging from 20 to 80% of their one-repetition maximum (1-RM). Subsequently, participants will be further randomised into two groups: an intervention group receiving a dietary intervention targeting a daily protein intake of 1.2-1.5 g/kg/day (PRT-Pro), and a control group with no dietary intervention (PRT-only). The dietary protein intervention will include counselling sessions and the provision of protein-rich foods. DISCUSSION: This study aims to elucidate the effect of various PRT intensities and the supplementary effects of adequate dietary protein intake on muscle mass, muscle strength, and physical performance in frail older adults. The results will provide critical insights for scientists and healthcare professionals, facilitating the development of more effective strategies to combat sarcopenia and frailty in this population.

trial registrationThe trial is registered at the ICTRP (OMON trial ID NL8785).

Indexed as

Dietary ProteinsFrail ElderlyIndependent LivingResistance TrainingAgedAged, 80 and overFemaleHumansMaleMuscle StrengthRandomized Controlled Trials as TopicSarcopeniaDietary ProteinsAgeingFrailtyProtein intakeResistance exerciseSarcopenia

Identifiers

PMID40783689
PMCPMC12335769

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.