Evidence mapPaperPMID 40783741Full record

ReviewJournal of ovarian research2025

Comparative advantage and efficacy of natural products for polycystic ovary syndrome.

Jinsol Lee, Seonung An, Yeong Woo Kim, La Yoon Choi, Dae Yong Kim, Mi Hye Kim

Abstract readReview
In one paragraph

Review in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinsol LeeCollege of Korean Medicine, Woosuk University, Jeonju, 54986, Republic of Korea.
Seonung AnCollege of Korean Medicine, Woosuk University, Jeonju, 54986, Republic of Korea.
Yeong Woo KimCollege of Korean Medicine, Woosuk University, Jeonju, 54986, Republic of Korea.
La Yoon ChoiCollege of Korean Medicine, Woosuk University, Jeonju, 54986, Republic of Korea.
Dae Yong KimCollege of Korean Medicine, Woosuk University, Jeonju, 54986, Republic of Korea.
Mi Hye KimCollege of Korean Medicine, Woosuk University, Jeonju, 54986, Republic of Korea. kimmh526@woosuk.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNatural products including Korean Medicine, Traditional Chinese Medicine and Campo medicine have been suggested to be suitable for polycystic ovary syndrome (PCOS), which is known to be a multifactorial disease, since current treatment for PCOS focuses on the amelioration of symptoms with adverse effects. AIM OF THE STUDY: In this review, the ethnopharmacology and mechanisms of natural remedies including herbs, herbal formulation and acupunctures are introduced, providing a comprehensive insight for its advantage on PCOS. MATERIALS AND

methodsWe conducted a comprehensive literature search using PubMed, MEDLINE, and Google Scholar databases. Search terms included combinations of "polycystic ovary syndrome," "PCOS," "natural product," "herbal medicine," "phytotherapy," "acupuncture," and "alternative and complementary medicine".

resultsA total of 2,514 articles were identified. After removing duplicates, we screened titles and abstracts for relevance. Studies were included if they involved: (1) preclinical in vivo or in vitro experiments using natural products in PCOS models; (2) randomized controlled trials (RCTs) or meta-analyses involving herbal, acupuncture, or combined treatments for PCOS; or (3) mechanistic evaluations. A total of 69 studies were selected for full-text analysis. Articles were excluded if they were non-original (e.g., reviews, commentaries), unrelated to PCOS, or did not include natural treatment modalities.

conclusionThe current status of the potential target pathway of natural products was assigned to three categories: research on the improvement of ovary and uterus quality, fertility and the weight loss for PCOS. However, there is no continuous study from basic research including in vitro and in vivo, and clinical trials. Large scale and more in-depth research are needed to verify their potential benefits for treating PCOS as a new drug.

Indexed as

Biological ProductsPolycystic Ovary SyndromeAcupuncture TherapyAnimalsFemaleHumansPhytotherapyTreatment OutcomeBiological ProductsAlternative and complementary medicineHerbal medicineMode of actionNatural productPolycystic ovary syndrome

Identifiers

PMID40783741
PMCPMC12335035

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.