Observational studyPeerJ2025
Compatibility of endoscopic examination using i-scan technology with histopathology results in laryngeal carcinoma: prospective observational study.
Observational study in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Laryngeal carcinoma is a type of cancer that occurs in the laryngeal tissue with a high mortality rate. Fiber optic laryngoscopy examination with i-scan is a non-invasive technology used to visualize changes in the structure of the mucosa and blood vessels, aiding in better identification of malignancies. Despite its promising potential, the routine use of i-scan technology in examinations is not yet established in Indonesia, especially West Java. Objective: To compare endoscopic findings using i-scan with histopathological results in patients with laryngeal carcinoma. Methods: This study is an analytical prospective observational research with a cross-sectional design, followed by a concordance test analysis using accuracy tests and the kappa index. The data collected include information from all laryngeal tumor patients at the ORLHNS outpatient clinic at Dr. Hasan Sadikin General Hospital from July to December 2023. Results: This prospective observational study evaluated i-scan endoscopy's diagnostic accuracy versus histopathology in 29 laryngeal carcinoma patients, demonstrating 96% sensitivity (95% CI [80.4-99.3%]) and 100% specificity (95% CI [39.8-100%]) with substantial histopathological agreement ( Conclusion: Our findings demonstrate concordance between i-scan endoscopic examination and histopathological results in laryngeal carcinoma evaluation. While this study provides preliminary evidence supporting the potential utility of i-scan technology for early lesion identification and biopsy targeting, further validation through larger-scale multicenter studies is warranted to confirm its clinical applicability.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.