Evidence map›Paper›PMID 40786231›Full record

ReviewScience and technology of advanced materials2025

Thylakoids for enhanced photodynamic therapy in hypoxic tumours.

Tong Yin, Jingyu Liu, Yue Wu, Xiaobo Peng, Zhibin Hao, Jingxi Zhang, Xianbao Zhan

Abstract readReview
In one paragraph

Review in Science and technology of advanced materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tong YinDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.
Jingyu LiuDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.
Yue WuDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.
Xiaobo PengDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.
Zhibin HaoDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.
Jingxi ZhangDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.
Xianbao ZhanDepartment of Oncology, Changhai Hospital, Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current tumor therapies face significant limitations such as hypoxic microenvironments, systemic toxicity, and immunosuppression. Thylakoid-based nanomaterials strategically integrate the structural-functional properties of natural biological components with the versatility of nanotechnology. These biomaterials have garnered substantial scientific interest due to their promising therapeutic potential in oncology. Thylakoids perform essential biological functions including solar energy absorption, photolytic oxygen generation, and operation of photosynthetic electron transport chains. Harnessing thylakoid-specific photochemical properties through nanoscale hybridization offers an innovative paradigm for developing multifunctional platforms in oncotherapy. This review summarizes current challenges in tumor therapy and the advantages of thylakoid-based nanomaterials in addressing these limitations. We further examine recent advances in the engineering design of thylakoid-based nanomaterials and their therapeutic applications. Finally, we discuss existing challenges and future prospects in this field.

Indexed as

hybrid nanosystemsphotosynthetic therapyreactive oxygen speciesThylakoid-based nanomaterialstumor hypoxia modulation

Identifiers

PMID40786231
PMCPMC12333001

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.