Evidence map›Paper›PMID 40786390›Full record

ArticleCureus2025

Absorption, Scintigraphy, Efficacy and Tolerability of Short-Term Calcium Carbonate Supplementation in Healthy Subjects.

Gaurav K Jain, Nazeer Hasan, Nilesh Chandra, Abha Mishra

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gaurav K JainDepartment of Pharmaceutics, Centre for Advanced Formulation Technology, Delhi Pharmaceutical Sciences and Research University, New Delhi, IND.
Nazeer HasanDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, IND.
Nilesh ChandraDivision of Discovery Research, Indian Council of Medical Research Head Quaters, New Delhi, IND.
Abha MishraDepartment of Physiology, Jodhpur Institute of Engineering and Technology, Medical College and Hospital, Jodhpur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orally administered calcium carbonate tablets are commonly prescribed as a calcium supplement, and their short-term use is popular among the healthy population. However, being a nutritional supplement, the in vitro properties and clinical efficacy of calcium carbonate supplements are sometimes compromised. The present study aimed to assess the absorption, in vivo dispersion, efficacy and tolerance of Gemcal DS tablet following its short-term use for four weeks. Post-dosing, a gradual rise in serum calcium concentration was observed and the peak increment in serum calcium (4.13±0.38 µg/mL) was reached at four hours. The bioavailability, determined as the area under the curve for six hours (ΔAUC

Indexed as

absorptionbone densitybone markercalcium carbonateefficacyin vitro dissolutionparathyroid hormonepharmacokineticsscintigraphytolerance

Identifiers

PMID40786390
PMCPMC12335733

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.