Evidence map›Paper›PMID 40786606›Full record

ReviewFrontiers in cellular and infection microbiology2025

Anaerobic gut bacteria and their potential role in the initiation, exacerbation, and development of human colorectal cancer: a narrative review.

Sahar Sabour, Hanieh Sadeghi Koupaei, Hadi Ghasemi, Mansour Amin, Taher Azimi

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Recent advances in the positive role ofFrontiers in immunology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sahar SabourInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Hanieh Sadeghi KoupaeiPediatric Congenital Hematologic Disorders Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hadi GhasemiHIV/AIDS Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Mansour AminInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Taher AzimiDepartment of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is known as the second leading cause of cancer-related deaths around the world. Rectal bleeding, changes in bowel movements, weight loss, and fatigue are the main clinical presentations of CRC. While the exact etiology of the disease is unknown, CRC is considered a complex and multifactorial disease resulted from an intricate interplay of genetic and environmental factors. Moreover, CRC is known as a chronic inflammation-associated tumor, and patients with inflammatory bowel disease (IBD) or Irritable bowel syndrome (IBS) are susceptible groups to CRC development. The gut microbiota and its metabolites play a crucial role in the development and progression of CRC. CRC can be created after anaerobic bacterial infections such as Enterotoxigenic

Indexed as

Bacteria, AnaerobicBacterial InfectionsColorectal NeoplasmsGastrointestinal MicrobiomeCarcinogenesisHumansanaerobic gut bacterialcolorectal cancerCRCgut bacterialnarrative review

Identifiers

PMID40786606
PMCPMC12331651

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.