ArticleFrontiers in pain research (Lausanne, Switzerland)2025
Anti-nociceptive properties of cardiopulmonary baroreceptors in patients with chronic back pain.
Article in Frontiers in pain research (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Pressure point: blood flow restriction exercise and the pain paradox in musculoskeletal injury and persistent pain populations-a narrative review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Association between altered baroreflex control and pain intensity in fibromyalgia.BMC neurology · 2025Article
- Chronic pain: a modifiable target to reduce perioperative cardiovascular morbidity.British journal of anaesthesia · 2025Article
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6 authors.
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Abstract
Introduction: Reduced pain perception following a persistent noxious stimulus during a study session (short-term habituation) is believed to be partially mediated by descending inhibitory mechanisms, although these mechanisms have not been fully elucidated. We examined the hypothesis that cardiopulmonary baroreceptor would significantly increase short-term habituation in chronic back pain (CBP) patients. Methods: A short-term habituation protocol was utilized that involved 1-sec pulses (×10) at 105% heat pain threshold on the anterior forearm at 0.5 Hz. Cardiopulmonary baroreceptor unloading was performed via lower body negative pressure (LBNP) that reduces central venous pressure to elicit a reflex increase in sympathetic nerve activity. Results: Short-term habituation was observed in young, healthy participants ( Conclusions: Together, these findings demonstrate an association between cardiopulmonary baroreceptor unloading and a reduction in pain perception during repetitive noxious stimuli in CBP patients, particularly among CBP patients with greater pain severity.
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