Evidence map›Paper›PMID 40786643›Full record

ArticleWellcome open research2024

A range of voltage-clamp protocol designs for rapid capture of hERG kinetics.

Chon Lok Lei, Dominic J Whittaker, Monique J Windley, Matthew D Perry, Adam P Hill, Gary R Mirams

Abstract read
In one paragraph

Article in Wellcome open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Evaluating the predictive accuracy of ion-channel models using data from multiple experimental designs.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chon Lok LeiUniversity of Macau Institute of Translational Medicine, Taipa, Macao.
Dominic J WhittakerUniversity of Nottingham School of Mathematical Sciences, Nottingham, England, NG7 2RD, UK.ORCID https://orcid.org/0000-0002-2757-5491
Monique J WindleyComputational Cardiology Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.ORCID https://orcid.org/0000-0001-6829-3856
Matthew D PerryUniversity of New South Wales School of Biomedical Sciences, Sydney, New South Wales, Australia.
Adam P HillComputational Cardiology Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Gary R MiramsUniversity of Nottingham School of Mathematical Sciences, Nottingham, England, NG7 2RD, UK.ORCID https://orcid.org/0000-0002-4569-4312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We provide details of a series of short voltage-clamp protocols designed for gathering a large amount of information on hERG (K

Indexed as

computational modelexperimental designion channelmathematical modelpatch clamp

Identifiers

PMID40786643
PMCPMC12334913

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.