Evidence map›Paper›PMID 40787133›Full record

ArticleJournal of dental anesthesia and pain medicine2025

Effect of low-level laser therapy on pain perception and anxiety levels in conventional local anesthesia injection.

Lalasa Gaddam, Deepa Anumala, Kishore Kumar Katuri, Divya Pedapudi, Shaik Shazia Begum, Ramanarayana Boyapati

Abstract read
In one paragraph

Article in Journal of dental anesthesia and pain medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lalasa GaddamDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0006-7762-0269
Deepa AnumalaDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0000-0003-4334-8173
Kishore Kumar KaturiDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0000-0003-2002-4352
Divya PedapudiDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0004-4845-9774
Shaik Shazia BegumDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0004-2737-662X
Ramanarayana BoyapatiDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0000-0002-9196-0183

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The goal of dental practice is to ensure painless treatments. This study aimed to assess the effectiveness of Low-level Laser Therapy (LLLT) in reducing pain perception and anxiety associated with conventional local anesthetic injections. Methods: This was a randomized, single-blind, split-mouth study involving 36 participants divided into two groups. Group I underwent LLLT prior to local anesthesia injection, whereas Group II underwent the procedure without laser activation. Anxiety levels were measured using the Hamilton Anxiety Rating Scale (HAM-A), and pain was evaluated using the Visual Analog Scale (VAS) and Wong-Baker Faces Rating Scale (WBFRS). Results: Statistical analyses were performed using the SPSS 22 software (IBM, Armonk, NY, USA). Post-intervention analysis of the HAM-A scores showed a reduction in anxiety levels following LLLT, with mild anxiety increasing from 52.8% to 69.44%, and moderate anxiety decreasing from 47.2% to 30.56%. In terms of pain assessment, VAS scores revealed that 38.9% of patients in Group I reported no pain compared to 0% of patients in Group II. Moderate pain was reported by 50% of patients in Group I and 75% of patients in Group II, while severe pain was reported by 11.1% and 25% of patients, respectively. Pain distribution (WBFRS) showed that 63.9% of patients in Group I reported no pain versus 0% of patients in Group II. Little pain was experienced by 36.1% of Group I and 58.3% of Group II patients, whereas 41.7% of Group II patients reported slightly more pain. Statistical comparison showed that Group I had significantly lower mean VAS (1.72 ± 0.659) and WBFRS (1.36 ± 0.487) scores than Group II (VAS: 2.25 ± 0.439; WBFRS: 2.42 ± 0.500), with both results being statistically significant (P < 0.001). Conclusion: LLLT was effective in reducing pain associated with injections. It can be used successfully to manage procedures that patients commonly perceive as painful, thereby providing a natural analgesic effect. Additionally, LLLT contributes to creating positive treatment experiences, which play a key role in fostering a long-term, trusting relationship between the patient and clinician.

Indexed as

AnxietyLocal AnesthesiaLow-level Laser TherapyPain Perception

Identifiers

PMID40787133
PMCPMC12328132

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.