Evidence map›Paper›PMID 40787585›Full record

ArticleInternational journal of women's health2025

Analyzing Influencing Factors of Uterine Rupture in Pregnant Women with Scarred Uterus Undergoing Repeat Delivery and Evaluating the Predictive Value of Lower Uterine Anterior Wall Thickness.

Liying Zhang, Ting Li, Pengming Zhang, Chunjuan Li

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Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Liying Zhang *Department of Ultrasound Medicine, Zhangjiakou First Hospital, Zhangjiakou, Hebei Province, 075000, People's Republic of China.
Ting Li *Department of Ultrasound Medicine, Zhangjiakou First Hospital, Zhangjiakou, Hebei Province, 075000, People's Republic of China.ORCID 0009-0008-2678-5121
Pengming ZhangDepartment of Ultrasound Medicine, Zhangjiakou First Hospital, Zhangjiakou, Hebei Province, 075000, People's Republic of China.
Chunjuan LiDepartment of Obstetrics and Gynecology, Chongli Hospital, Peking University Third Hospital, Beijing, 076350, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze influencing factors of uterine rupture in pregnant women with a scarred uterus undergoing repeat delivery and to investigate the predictive value of transabdominal ultrasound measurement of lower uterine anterior wall thickness. Methods: A retrospective analysis of 159 pregnant women with scarred uterus (March 2022-May 2024) divided into rupture group (n=48) and non-rupture group (n=111). Lower uterine anterior wall thickness was measured via transabdominal ultrasound pre-delivery. Univariate/multivariate logistic regression and ROC curves were used to identify risk factors and evaluate predictive performance. Results: The rupture group had higher rates of advanced maternal age, prenatal BMI ≥30 kg/m², multiparity, single-layer cesarean suturing, and shorter inter-pregnancy intervals (all P<0.05). Lower uterine anterior wall thickness was significantly thinner in the rupture group (1.24±0.31 mm vs 2.19±0.52 mm, P<0.001). Multivariate analysis identified thinner lower uterine anterior wall thickness (OR=2.359, 95% CI:1.362-4.134) and single-layer suturing (OR=1.863, 95% CI:1.125-3.086) as independent risk factors, while longer inter-pregnancy interval was protective (OR=0.256, 95% CI:0.091-0.634; all P<0.05). ROC analysis showed AUCs of 0.821 (scar thickness), 0.783 (single-layer suturing), and 0.759 (inter-pregnancy interval); combined prediction achieved an AUC of 0.894 (95% CI:0.837-0.946), sensitivity 90.23%, specificity 84.15%. Uterine rupture was associated with worse perioperative outcomes (eg, higher transfusion rates, longer hospitalization) and adverse neonatal outcomes (lower birth weight, more preterm births; all P<0.05). Conclusion: Lower uterine anterior wall thickness, single-layer suturing, and inter-pregnancy interval are key determinants of uterine rupture. Combined assessment of these factors provides high predictive accuracy (AUC=0.894) and improves risk stratification.

Indexed as

lower uterine anterior wall thicknesspredictive valuerisk factorsscarred uterusuterine rupture

Identifiers

PMID40787585
PMCPMC12333656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.