Evidence map›Paper›PMID 40788176›Full record

ReviewTherapeutic delivery2025

Unlocking the full potential of piperine-loaded nanocarriers for cancer treatment.

Girish Kumar, Beatriz Ruivinho, Tarun Virmani, Pedro Brandão, Priti Choudhary, Neeraj Kumar Chouhan, Manish Kumar, Abhishek Sharma, Md Sayeed Akhtar, Obaid Afzal and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Therapeutic delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Girish KumarAmity Institute of Pharmacy, Amity University, Greater Noida, India.
Beatriz RuivinhoDepartment of Chemistry and Pharmacy, Faculty of Sciences and Technology, University of Algarve, Faro, Portugal.
Tarun VirmaniAmity Institute of Pharmacy, Amity University, Greater Noida, India.
Pedro BrandãoiBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, University of Lisboa, Lisbon, Portugal.
Priti ChoudharySchool of Medical & Allied Sciences, K.R. Mangalam University Sohna Road, Gurugram, Haryana, India.
Neeraj Kumar ChouhanAmity Institute of Pharmacy, Amity University, Greater Noida, India.
Manish KumarAmity Institute of Pharmacy, Amity University, Greater Noida, India.
Abhishek SharmaAmity Institute of Pharmacy, Amity University, Greater Noida, India.
Md Sayeed AkhtarDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Sadaf FarooquiDepartment of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Sofia O D DuarteiBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, University of Lisboa, Lisbon, Portugal.
Pedro FonteDepartment of Chemistry and Pharmacy, Faculty of Sciences and Technology, University of Algarve, Faro, Portugal.ORCID 0000-0002-1115-9282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the twenty-first century, cancer continues to be a significant worldwide health concern that requires immediate and ongoing attention. Currently, chemotherapeutic treatments are constrained by various limitations, including drug resistance, nonspecific distribution, and organ toxicity. These difficulties highlight the need for safer and more efficient substitutes, like Piperine (PPN), a bioactive alkaloid obtained from

Indexed as

AlkaloidsAntineoplastic AgentsAntineoplastic Agents, PhytogenicBenzodioxolesDrug CarriersNanoparticlesNeoplasmsPiperidinesPolyunsaturated AlkamidesAnimalsBiological AvailabilityDrug Delivery SystemsHumansAlkaloidsAntineoplastic AgentsAntineoplastic Agents, PhytogenicBenzodioxolesDrug CarriersPiperidinespiperinePolyunsaturated AlkamidesCancerchemotherapyliposomenanoparticlenanostructured lipid carrierpiperinepolymersolid lipid nanoparticle

Identifiers

PMID40788176
PMCPMC12502809

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.