ArticleMedical science monitor : international medical journal of experimental and clinical research2025
Electrocardiographic Indicators of Left Atrial Remodeling in Ischemic Stroke Patients with Atrial Fibrillation.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Left atrial (LA) remodeling (LAR) is a risk factor for atrial fibrillation (AF) and ischemic stroke (IS). LAR can be detected on electrocardiogram (ECG) by P wave indices. The aim of this study was to search for noninvasively assessed LAR markers associated with the history of IS in patients with AF, considering differences between males and females. MATERIAL AND METHODS This retrospective study included a group of 256 patients, aged 76.19 (±9.64) years, with documented AF and after IS. The control group consisted of 70 people aged 68.43 (±7.38) years with AF but without IS. The collected study material included ECG (longest P wave duration [Pmax], P wave duration [PWD], P wave dispersion [PWDI], P wave terminal force in lead V₁ [PWTFV₁], negative phase duration of the P in V₁ [PWDNV1]) and trans-thoracic echocardiography. Results were compared among both sexes and the control group. RESULTS In the study group, electrophysiological LAR was more advanced than in the control group, with significantly higher PWDI (80.60(±23.05) vs 62.49(±14.92) ms; p<0.001) and lower percentage of patients with normal Pmax/PWTFV1/PWDNV1/PWDI indices (2.73 vs 11.43%; p<0.05) respectively. LA area was larger (28.33(±7.50) vs 21.26(±2.79) cm²; p<0.001) and LVEF was lower (54.85(±9.14) vs 58.17(±6.40); p<0.05) in the study group compared to the control group. PWTF (4801.6(±3695.4) vs 4127.8(±3689.6) mcV*ms; p=0.049) was higher in males than in females. In multivariable logistic regression analysis, predictors significantly associated with IS occurrence in patients with AF were: higher PWDV₁ values (95% CI: 1.02-1.08, p<0.001), Pmax (95% CI: 0.90-0.97, p<0.001), and LVEF (95% CI: 0.84-0.99, p=0.030). CONCLUSIONS In patients with IS, higher indices of both structural and electrophysiological LAR are observed. There are significant differences between the sexes in the severity of LAR indices.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.