ArticleUltrasonography (Seoul, Korea)2025
Impact of an immediate short waiting period on ultrasound-based ablative margin assessment following radiofrequency ablation for hepatocellular carcinoma.
Article in Ultrasonography (Seoul, Korea), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ultrasound-guided ablation of hepatocellular carcinoma: a review of its past, present, and future.Ultrasonography (Seoul, Korea) · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
purposeThis study aimed to evaluate whether an immediate short waiting period after radiofrequency ablation (RFA) can improve the accuracy of ultrasound (US)-based assessment of the ablation zone in patients with hepatocellular carcinoma (HCC).
methodsA prospective cohort study was conducted involving 41 patients who underwent US-guided RFA for HCC. Tumor margin conspicuity, electrode tip visibility, and operator confidence in assessing the ablative margin were recorded immediately following electrode deactivation and at 1-minute intervals for 5 minutes. Post-ablation computed tomography was performed to confirm the sufficiency of the ablative margins. The Friedman test and post-hoc Conover analysis were used to assess changes over time.
resultsOver time, significant improvements were observed in tumor margin visibility, electrode tip visualization, and operator confidence in ablative margin assessment (all P<0.001). Repositioning and additional ablation were required in 29.3% (12/41) of patients, with all achieving sufficient ablative margins. Larger tumor size was associated with decreased operator confidence (P=0.008). No major complications occurred.
conclusionA short waiting period following RFA enhances the visibility of tumor margins and electrode tips on US, thereby increasing operator confidence in assessing ablative margin sufficiency. Implementing an immediate short waiting period may improve the accuracy of treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.