Evidence map›Paper›PMID 40791111›Full record

ReviewAnalytical chemistry2025

Advances toward At-Home Measurements of Complete Blood Cell Counts and Other Hematological Parameters.

Allison J Tierney, Charles R Mace

Abstract readReview
In one paragraph

Review in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Allison J TierneyDepartment of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Charles R MaceDepartment of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.ORCID 0000-0003-3410-5014

Funding

Precision metering and autonomous separation of blood components for pre-clinical microsampling at the point-of-careR01EB035549 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI Charles R Mace · 2025 to 2026
$1.1M
NIBIB NIH HHS R01 EB035549
6 · The paper itself

Abstract

The ability to perform complete blood count (CBC) testing in at-home settings could transform patient care by enabling earlier detection of diseases, improving the management of chronic diseases, and reducing the burden on healthcare facilities. However, transitioning CBCs─or key components of them─outside of a clinical laboratory can present significant challenges, particularly in maintaining the analytical performance necessary for clinical utility. In this Perspective, we explore emerging technologies aimed at bringing CBC testing closer to patients. We discuss how accuracy and precision are reported for different technologies and the current advancements in portable and at-home CBC technologies, all while identifying both successes and gaps in current solutions. Additionally, we highlight innovations in point-of-care sample collection that facilitates remote clinical laboratory analysis. By emphasizing quantitative performance metrics, we aim to define critical research priorities for future home-based CBC devices. While no single solution currently meets all analytical and practical demands, ongoing technological advancements continue to drive progress toward reliable and accessible decentralized CBC testing.

Indexed as

Blood Cell CountPoint-of-Care SystemsHumans

Identifiers

PMID40791111
PMCPMC12698234

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.