ArticleHuman vaccines & immunotherapeutics2025
Pandemic paradox: How the COVID-19 crisis transformed vaccine hesitancy into a two-edged sword.
Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Upward intergenerational support and vaccination decisions among community-dwelling older adults in China: A multicenter qualitative study.Human vaccines & immunotherapeutics · 2026Article
- The Relationship Between COVID-19 Vaccine Regret, Distrust of the Healthcare System, and Future Vaccine Intentions.Journal of evaluation in clinical practice · 2026Article
- Article
- Building on Vaccine Confidence in the Aftermath of the Pandemic: A Qualitative Study in Primary Care Physicians.Vaccines · 2026Article
- Psychosocial and Social Security Risks Linked to Vaccine Misinformation in Romania: Implications for Vaccination Acceptance and Public Policy.Behavioral sciences (Basel, Switzerland) · 2026Article
- Addressing Knowledge, Attitudes and Practices Toward Dengue Fever, Vector Control, and Vaccine Acceptance Among the General Population in Singapore.Tropical medicine and infectious disease · 2026Article
- Systematic Review: Efficacy, Safety Profile, and Cost-Effectiveness of Nirsevimab Versus Palivizumab for RSV Prevention in Children Under 24 Months.Children (Basel, Switzerland) · 2026Review
- Hesitancy towards the COVID-19 booster vaccination: a thematic analysis from a focus group study in Spain.BMC public health · 2026Article
- COVID-19 Information Sources and Vaccination Status Among Californian Adults by Generation Using the 2022 California Health Interview Survey: Cross-Sectional Study.JMIR public health and surveillance · 2026Article
- Article
- Improving Vaccine Knowledge Among Adolescents: A Pre-Post School-Based Educational Intervention in Southern Italy.Vaccines · 2026Article
- Vaccination Strategies Against Respiratory Pathogens in the Adult Population: A Narrative Review.Vaccines · 2026Review
- Bridging immunization and oral health: a role for paediatric dentists in mitigating vaccine hesitancy in Africa.Frontiers in oral health · 2026Article
- Mobility between communities can reduce the impact of measles intervention during an outbreak: a mathematical modeling study.Frontiers in public health · 2026Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rapid development of COVID-19 vaccines was a landmark achievement that saved millions of lives. However, this success also intensified vaccine hesitancy, as misinformation, evolving public health guidelines, and growing distrust in institutions fueled anti-vaccine sentiment. In this opinion piece, we explore the paradoxical legacy of the COVID-19 vaccination campaign - how a global scientific triumph simultaneously gave rise to an emboldened anti-vaccine movement. Drawing on international data, we highlight the association between baseline vaccine acceptance and subsequent booster uptake and interpret these trends through the lens of the Health Belief Model. We further examine the psychological, cultural, political, and structural drivers of hesitancy and outline key strategies to rebuild public trust. Addressing this crisis requires proactive, evidence-informed, and culturally sensitive approaches to safeguard the future of global immunization efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.