Evidence map›Paper›PMID 40791135›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

A Sensitive Ratiometric Thermometer Constructed by AIEgen-Based Mixed Lanthanide MOF for Intracellular Temperature Mapping.

Zhijia Li, Jieping Zhang, Zhiyuan Wu, Hang Lei, Yunfang Zhao, Wenqiu Qi, Xue Gao, Feilong Jiang, Yongsheng Liu, Lian Chen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhijia LiFujian Science and Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, Fujian, 350108, China.ORCID https://orcid.org/0009-0009-2577-054X
Jieping ZhangState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Zhiyuan WuState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Hang LeiState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Yunfang ZhaoState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Wenqiu QiState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Xue GaoState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Feilong JiangState Key Laboratory of Structure Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
Yongsheng LiuFujian Science and Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, Fujian, 350108, China.
Lian ChenFujian Science and Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, Fujian, 350108, China.ORCID https://orcid.org/0000-0002-9741-022X
Maochun HongFujian Science and Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, Fujian, 350108, China.

Funding

National Key Research and Development Program 2023YFF0713600National Natural Science Foundation of China 22271280National Natural Science Foundation of China 92361202Natural Science Foundation of Fujian Province 2023J05086
6 · The paper itself

Abstract

Accurate temperature sensing at the subcellular level is of great significance for gaining insights into a wide range of biological processes. Aggregation-induced emission (AIE) is a promising photophysical phenomenon in which the luminescence intensity is highly related to the degree of restriction of intramolecular motions. By combining AIE luminogen (AIEgen) ligands with mixed lanthanide ions, an AIEgen-based mixed lanthanide MOF (LnMOF) can be synthesized. In this unique MOF matrix, the vibrations of pendant phenyl rings in the AIEgen ligands are particularly sensitive to temperature changes, rendering the mixed LnMOF highly sensitive as a ratiometric thermometer. Within the physiological temperature range (291-321 K), the maximum relative sensitivity (S

Indexed as

Lanthanoid Series ElementsMetal-Organic FrameworksThermometersThermometryAnimalsHeLa CellsHumansMiceTemperatureLanthanoid Series ElementsMetal-Organic Frameworksbioimagingintracellular temperature mappingmetal–organic frameworksratiometric fluorescence thermometer

Identifiers

PMID40791135
PMCPMC12591144

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.