ArticlebioRxiv : the preprint server for biology2025
Distinct Synaptic Mechanisms Drive
Jay English, Danny McSweeney, Jinghui Geng, Ethan Howell, Fumiko Ribbe, Matthew Hinderhofer, Lydia Proskauer, Rebecca Sebastian, Le Wang, Tal Sharf and 2 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Jay EnglishDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Danny McSweeneyDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Jinghui GengDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064.
Ethan HowellDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Fumiko RibbeDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Matthew HinderhoferDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Lydia ProskauerDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Rebecca SebastianDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.
Le WangDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064.
Tal SharfDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064.
Zhiping P PangDepartment of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, New Brunswick, NJ 08901.ORCID 0000-0002-6183-1233 ChangHui PakDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst MA 01003.ORCID 0000-0003-4192-7665 Funding
Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9MMolecular dissection of synaptic dysfunction in mental disordersR01MH122519 · NIMH · UNIVERSITY OF MASSACHUSETTS AMHERST · PI PAK, CHANGHUI · 2020 to 2024
$2.3MNIGMS NIH HHS T32 GM135096NIMH NIH HHS R01 MH122519
6 · The paper itselfAbstract
Copy number deletions in the 2p16.3/
Indexed as
Autism spectrum disordersE-I balanceHD-MEAshuman iPSCsinduced neuronsNRXN1schizophreniasynapsesynaptic transmission
Identifiers
PMID40791539
PMCPMC12338733
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390