Evidence mapPaperPMID 40792010Full record

SynthesisPeerJ2025

Effects of different exercise types on vascular endothelial function in individuals with abnormal glycaemic control: a systematic review and network meta-analysis.

Zongxiang Li, Shengyao Luo, Xuebing Bai, Lu Huang, Hongyan Guo, Song Chen, Dan Wang

Abstract readNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zongxiang LiFaculty of Physical Education and Art, Jiangxi University of Science and Technology, Ganzhou, China.
Shengyao LuoFaculty of Physical Education and Art, Jiangxi University of Science and Technology, Ganzhou, China.
Xuebing BaiFaculty of Physical Education and Art, Jiangxi University of Science and Technology, Ganzhou, China.
Lu HuangFaculty of Physical Education and Art, Jiangxi University of Science and Technology, Ganzhou, China.
Hongyan GuoFaculty of Physical Education and Art, Jiangxi University of Science and Technology, Ganzhou, China.
Song ChenFaculty of Physical Education and Art, Jiangxi University of Science and Technology, Ganzhou, China.
Dan WangProvincial University Key Laboratory of Sport and Health Science, School of Physical Education and Sport Sciences, Fujian Normal University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brachial artery flow-mediated dilation (FMD) is a key marker of endothelial function, often impaired in individuals with abnormal glycemic control. While exercise has been shown to improve brachial artery FMD, the relative efficacy of different exercise modalities remains unclear. This study employed a network meta-analysis (NMA) to compare the effects of various types of exercise on FMD. Methods: A comprehensive search of PubMed, Embase, Cochrane, Web of Science, and EBSCO databases identified randomized controlled trials evaluating the effects of exercise on brachial artery FMD up to January 2025. Two independent reviewers screened studies, extracted data, and assessed risk of bias. Eligible studies were assessed for bias using version 2 of the Cochrane Risk of Bias tool. Stata 16.0 was used for the NMA. Results: Seventeen studies with 797 participants (prediabetes: 76; T2DM: 721) were included. Aerobic interval exercise (AIE) significantly improved FMD (MD = 2.23%, 95% CI [1.0 9%-3.37%], Conclusion: AIE was the most effective modality for improving FMD, with MBE serving as a viable alternative for individuals with lower fitness or cardiovascular concerns. CE and ACE also provided benefits, while RE was less effective. Future studies should focus on long-term outcomes and personalized exercise strategies.

Indexed as

Diabetes Mellitus, Type 2Endothelium, VascularExerciseExercise TherapyGlycemic ControlPrediabetic StateBrachial ArteryHumansRandomized Controlled Trials as TopicVasodilationEndothelial functionExerciseFMDNetwork meta-analysisPrediabetesType 2 diabetes

Identifiers

PMID40792010
PMCPMC12338059

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.