Evidence map›Paper›PMID 40794147›Full record

ReviewProbiotics and antimicrobial proteins2026

Probiotics and Diet Modifications: A Holistic Approach to Tackling Helicobacter pylori with the Help of the Gut Microbiota.

Tamer A Addissouky, Yuliang Wang, Ibrahim El Tantawy El Sayed, Naser A Naser, Mohammed Jalal AlAhmed

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamer A AddissoukyDepartment of Biochemistry, Science Faculty, AL-Mustaqbal University, 51001, Hillah, Babylon, Iraq. tedesoky@gmail.com.
Yuliang WangJoint International Research Laboratory of Metabolic and Developmental Sciences, Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Ibrahim El Tantawy El SayedBiochemistry Branch, Department of Chemistry, Science Faculty, Menoufia University, Menoufia, Egypt.
Naser A NaserDepartment of Biochemistry, Science Faculty, AL-Mustaqbal University, 51001, Hillah, Babylon, Iraq.
Mohammed Jalal AlAhmedInstitute of Nutrition and Food Sciences, Al-Zaytoonah International University, Azaz, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHelicobacter pylori (H. pylori) is a common gastrointestinal pathogen that can persist for decades and lead to diseases like gastritis, peptic ulcers, and gastric cancer. Conventional antibiotic treatments have limitations like resistance and side effects, requiring alternative therapies. The gut microbiota may influence H. pylori colonization and eradication success. Strategies like probiotics, prebiotics, diet, and lifestyle changes may modulate the gut microbiota composition and function to inhibit H. pylori growth. Specific probiotic strains produce antimicrobial compounds, modulate immune responses, and alter gut microbiota in ways that can promote H. pylori eradication. Diets high in fiber, polyphenols, omega-3s, and fermented foods appear to inhibit H. pylori by supporting growth of beneficial bacteria. Lifestyle factors like stress, smoking, and alcohol negatively impact the gut microbiota. Personalized therapies based on the gut microbiome could optimize eradication rates.

conclusionThe gut microbiota represents a promising target for enhancing H. pylori eradication. Further research on microbiota-modulating therapies like probiotics, diet, and lifestyle changes may help develop more effective, personalized treatment approaches.

Indexed as

DietGastrointestinal MicrobiomeHelicobacter InfectionsHelicobacter pyloriProbioticsHumansLife StyleAntibiotic resistanceDiet modificationsGut microbiotaHelicobacter pyloriProbiotics

Identifiers

PMID40794147

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.