Evidence map›Paper›PMID 40795802›Full record

ArticleJournal of economic entomology2025

High-throughput chemical toxicity testing for beneficial insects: the value of coated vials.

Joshua A Thia, Julie Digard, Ashritha P S Dorai, Courtney Brown, Ary A Hoffmann

Abstract read
In one paragraph

Article in Journal of economic entomology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua A ThiaBio21 Institute, School of BioSciencses, The University of Melbourne, Melbourne, Australia.ORCID 0000-0001-9084-0959
Julie DigardBio21 Institute, School of BioSciencses, The University of Melbourne, Melbourne, Australia.ORCID 0009-0006-1101-0097
Ashritha P S DoraiBio21 Institute, School of BioSciencses, The University of Melbourne, Melbourne, Australia.ORCID 0009-0004-2928-039X
Courtney BrownBio21 Institute, School of BioSciencses, The University of Melbourne, Melbourne, Australia.ORCID 0000-0003-1515-1947
Ary A HoffmannBio21 Institute, School of BioSciencses, The University of Melbourne, Melbourne, Australia.ORCID 0000-0001-9497-7645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nontarget effects of insecticides used in agriculture can impact the ecosystem services provided by beneficial insects. Understanding the broader effects of chemical usage requires multispecies investigations on the impact of different insecticide active ingredients. In this work, we tested the utility of coated vials as a quick, cheap, and efficient dried residue chemical toxicity assay. This method was compared against dishes sprayed with a Potter tower, which is an industry standard instrument used to apply precise insecticide doses. Our study focused on 2 natural enemies of aphids, larval and adult stages of the Hippodamia variegata (Goeze 1777) ladybird beetle, and the parasitoid wasp, Diaeretiella rapae (McIntosh 1855). These natural enemies were exposed to multiple concentrations of 3 insecticides registered for aphid control in Australian agriculture: alpha-cypermethrin (pyrethroid), dimethoate (organophosphate), and sulfoxaflor (sulfoximine). Modelled concentration-response relationships showed evidence of general differences in the intercepts between methods, but not in slope (rate of mortality with concentration). However, these subtle statistically significant effects did not translate into marked differences in LC50-values, which were comparable across assay methods for all natural enemies and insecticides tested. Coated vials therefore produced estimates of chemical toxicity that were consistent with those derived from Potter tower sprays. This underscores the validity of coated vials as a method for performing high-throughput chemical toxicity experiments, as required when examining different populations of multiple taxa across a range of insecticide active ingredients.

Indexed as

ColeopteraHigh-Throughput Screening AssaysInsecticidesToxicity TestsWaspsAnimalsAphidsDimethoateLarvaPyrethrinsPyridinesSulfur CompoundsDimethoateInsecticidesPyrethrinsPyridinessulfoxaflorSulfur Compoundsacute toxicitybiological controlladybird beetlesnatural enemiesparasitoid waspsPotter tower

Identifiers

PMID40795802
PMCPMC12836096

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.