Evidence map›Paper›PMID 40796830›Full record

SynthesisBMC psychiatry2025

Suicidality among people with mild cognitive impairment: a sustematic review.

Alba Sánchez-Gil, Jesús Pérez, Víctor Navarro-López, Juan Luis Sánchez-González

Abstract readSystematic Review
In one paragraph

Synthesis in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alba Sánchez-GilNational Centre of Reference for People with Alzheimer's Disease and other Dementias, Salamanca, 37008, Spain.
Jesús PérezInstitute of Biomedical Research of Salamanca (IBSAL), Salamanca, 37007, Spain. jesusperez@usal.es.
Víctor Navarro-LópezFaculty of Health Sciences, Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Madrid, 28032, Spain.
Juan Luis Sánchez-GonzálezInstitute of Biomedical Research of Salamanca (IBSAL), Salamanca, 37007, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMild cognitive impairment (MCI) is a clinical stage between the expected cognitive decline of healthy ageing and dementia. People with MCI experience functional decline, social isolation and emotional symptoms that may increase suicidal thoughts and behaviours (STB). We aimed to explore the relationship between MCI and STB, as well as clinical and socioeconomic factors that may contribute to it.

methodsTo achieve our aims we carried out a comprensive systematic review of the existing scientific literature. We searched the following electronic databases up to June 2024: PubMed, Scopus, Cochrane Library, Web Of Science (WOS) and EMBASE. We employed the Cochrane Risk of Bias In Non-randomized Studies - of Exposure (ROBINS-E) and the Newcastle-Ottawa Scale to assess the quality of the eligible studies.

resultsAn initial search retrieved 1,176 publications; however, only 11 studies met eligibility criteria to be included in the final analysis. The quality of these studies ranged from 3 to 8 out of a maximum score of 9 in the Newcastle-Ottawa Scale, with a median score of 6. People with a formal diagnosis of MCI showed a higher prevalence of STB than those without such condition or with a more severe cognitive impairment. Comorbid psychiatric disorders, such as depression, other health problems, such as cardiovascular diseases, and a low socioeconomic status and/or poor educational background seemed to contribute to suicide risk in people with MCI.

conclusionOur systematic review suggests that people suffering MCI may be at an increased risk of presenting STB. Suicide prevention programmes for older populations with MCI should advocate for integrated health and social care models to tackle the clinical and social burden of suffering MCI.

Indexed as

Cognitive DysfunctionSuicidal IdeationSuicideHumansRisk FactorsMCIMild cognitive impairmentMortalitySuicide.Systematic review

Identifiers

PMID40796830
PMCPMC12341130

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.