Evidence mapPaperPMID 40796899Full record

ReviewItalian journal of pediatrics2025

Obesity‑related kidney disease: a review on ultrasound applications.

Armando Di Ludovico, Costanza Pucci, Giovanni Grassi, Gian Luca Chabert, Giuseppe Ledda, Ilaria Mascioli, Saverio La Bella, Francesca Ciarelli, Luciana Breda, Cosimo Giannini and 3 more

Abstract readReview
In one paragraph

Review in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Armando Di Ludovico *Department of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Costanza Pucci *Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Giovanni GrassiDepartment of Radiology, Azienda Ospedaliero Universitaria (A.O.U.) di Cagliari - Polo di Monserrato, Cagliari, Italy.
Gian Luca ChabertDepartment of Radiology, Azienda Ospedaliero Universitaria (A.O.U.) di Cagliari - Polo di Monserrato, Cagliari, Italy.
Giuseppe LeddaDepartment of Radiology, Azienda Ospedaliero Universitaria (A.O.U.) di Cagliari - Polo di Monserrato, Cagliari, Italy.
Ilaria MascioliDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Saverio La BellaDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Francesca CiarelliDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Luciana BredaDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Cosimo GianniniDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Angelika MohnDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Francesco ChiarelliDepartment of Pediatrics, University of Chieti"G. D'Annunzio", Chieti, Italy.
Antonio CorselloDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy. antonio.corsello@unimi.it.ORCID http://orcid.org/0000-0003-4578-0066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric obesity is a growing global health concern, associated with metabolic, cardiovascular, and kidney complications. Early identification and intervention are crucial to preventing long-term morbidity. This review examines the epidemiology, pathophysiology, and clinical implications of childhood obesity, focusing on its impact on kidney health. We discuss non-invasive diagnostic tools, including kidney ultrasound, and evidence-based management strategies. Obesity in children is linked to hypertension, insulin resistance, and early signs of kidney dysfunction, including increased kidney echogenicity and hyperfiltration. Ultrasound findings may serve as early markers of kidney involvement, potentially guiding risk stratification and intervention. Addressing pediatric obesity requires a multidisciplinary approach, incorporating lifestyle modifications, medical management, and early detection of organ damage. The aim of this narrative review is to summarize the pathophysiology of pediatric obesity-related kidney damage, current evidence on ultrasound-based screening, and possible diagnostic techniques. Further research is needed to validate ultrasound as a routine screening tool for obesity-related kidney disease in children.

Indexed as

Kidney DiseasesPediatric ObesityChildHumansUltrasonographyDopplerKidneyMetabolic syndromeNephrologyObesityPediatric ultrasound

Identifiers

PMID40796899
PMCPMC12344850

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.