ArticleRenal failure2025
Observation of the therapeutic effect of finerenone, a novel non-steroidal mineralocorticoid receptor antagonist, in patients with non-diabetic CKD.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Finerenone in IgA nephropathy: real-world 12-month propensity-matched cohort demonstrating proteinuria reduction, eGFR preservation, and safety profile.Renal failure · 2026Article
- Emerging therapeutic pipelines on kidney fibrosis: challenges in translational research.Journal of translational medicine · 2026Review
- Finerenone in non-diabetic CKD: an underexplored therapeutic opportunity.Renal failure · 2025Article
- Review
- Sodium-Glucose Cotransporter 2 Inhibitors in Lupus Nephritis and ANCA-Associated Vasculitis: Unmet Needs to be Addressed.Glomerular diseasesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, exhibits anti-fibrotic and anti-inflammatory properties. While numerous studies have demonstrated its efficacy in reducing kidney and cardiovascular events in diabetic kidney disease, data on non-diabetic chronic kidney disease (CKD) remain limited. This retrospective study evaluated the safety and efficacy of finerenone in adult patients with non-diabetic CKD. The primary study parameters included estimated glomerular filtration rate (eGFR), 24-h proteinuria, serum potassium (sK+), and serum albumin. A total of 78 patients met the eligibility criteria. Following finerenone treatment, the overall efficacy rate was 61.5% (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.