Trial reportJournal of pediatric gastroenterology and nutrition2025
Digital animation as a tool to enhance informed consent when recruiting infants with biliary atresia to a clinical trial.
Trial report in Journal of pediatric gastroenterology and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Digital animation as a tool to enhance informed consent when recruiting infants with biliary atresia to a clinical trial.Journal of pediatric gastroenterology and nutrition · 2025Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesParticipants may have a poor understanding of the research they are involved in due to the challenges of receiving information during acute illness and the complexity and length of participant information sheets. This study aimed to assess the impact and acceptability of using digital animation to recruit infants with biliary atresia to a clinical trial.
methodsThe mixed method design used questionnaires and interviews to assess the feasibility of using animation during recruitment to a feasibility trial (ISRCTN81936667). All participants received verbal and written information, and after the animation was introduced, participants additionally received the animation. Quantitative data are presented descriptively (median, frequencies), and recruitment before and after introducing the animation was compared using Fisher's exact test. Qualitative data were analysed thematically, and the combined quantitative and qualitative results were considered together.
resultsPerceptions of the animation were highly positive, with between 81.3% to 100% agreeing with positively framed statements and 87.5% to 100% disagreeing with negatively framed statements. However, there was no difference in numbers consenting to participate before (14/16, 87.5%) and after (16/18, 88.9%) introducing the animation (p = 1.00). Three qualitative themes emerged relating to the animation: technical accessibility, cognitive accessibility and enabling understanding.
conclusionsThe animation was viewed positively by participants who felt it increased understanding and enabled them to share information with others. Although this improved the informed consent process, it did not impact the consent rate. Digital animation could represent an effective way to present study information, better enabling participants to provide valid informed consent. CLINICAL
trial registrationTrial identifier: ISRCTN81936667.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.