Evidence map›Paper›PMID 40799384›Full record

ArticleACS pharmacology & translational science2025

Targeting Cathepsin K to Accelerate Diabetic Wound Healing.

Anne Chenchar, Vitoria Mattos Pereira, Anisha Apte, Bailey D Lyttle, Alyssa E Vaughn, Tanner Lehmann, James R Bardill, Carlos Zgheib, Kenneth W Liechty, Kelly C S Roballo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Fish Collagen Hydrolysates in Wound Healing: A Patent Review.ACS pharmacology & translational science · 2026
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anne ChencharSchool of Pharmacy, Biomedical Sciences Graduate Program, Department of Zoology and Physiology, Department of Animal Sciences, University of Wyoming, 1000 E. University Avenue, Laramie, Wyoming 82071, United States.
Vitoria Mattos PereiraSchool of Pharmacy, Biomedical Sciences Graduate Program, Department of Zoology and Physiology, Department of Animal Sciences, University of Wyoming, 1000 E. University Avenue, Laramie, Wyoming 82071, United States.
Anisha ApteLaboratory for Fetal and Regenerative Biology, Department of Surgery, College of Medicine, University of Arizona, 1656 E Mabel Street, Tucson, Arizona 85721, United States.
Bailey D LyttleLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado Denver, Anschutz Medical Campus and Children's Hospital Colorado, 12631 East 17th Avenue, Aurora, Colorado 80045, United States.
Alyssa E VaughnLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado Denver, Anschutz Medical Campus and Children's Hospital Colorado, 12631 East 17th Avenue, Aurora, Colorado 80045, United States.
Tanner LehmannLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado Denver, Anschutz Medical Campus and Children's Hospital Colorado, 12631 East 17th Avenue, Aurora, Colorado 80045, United States.
James R BardillLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado Denver, Anschutz Medical Campus and Children's Hospital Colorado, 12631 East 17th Avenue, Aurora, Colorado 80045, United States.ORCID https://orcid.org/0000-0002-6189-8438
Carlos ZgheibLaboratory for Fetal and Regenerative Biology, Department of Surgery, College of Medicine, University of Arizona, 1656 E Mabel Street, Tucson, Arizona 85721, United States.
Kenneth W LiechtyLaboratory for Fetal and Regenerative Biology, Department of Surgery, College of Medicine, University of Arizona, 1656 E Mabel Street, Tucson, Arizona 85721, United States.
Kelly C S RoballoSchool of Pharmacy, Biomedical Sciences Graduate Program, Department of Zoology and Physiology, Department of Animal Sciences, University of Wyoming, 1000 E. University Avenue, Laramie, Wyoming 82071, United States.
Zhaojie ZhangSchool of Pharmacy, Biomedical Sciences Graduate Program, Department of Zoology and Physiology, Department of Animal Sciences, University of Wyoming, 1000 E. University Avenue, Laramie, Wyoming 82071, United States.
Brenda M AlexanderSchool of Pharmacy, Biomedical Sciences Graduate Program, Department of Zoology and Physiology, Department of Animal Sciences, University of Wyoming, 1000 E. University Avenue, Laramie, Wyoming 82071, United States.
Sreejayan NairNutriwyo LLC, 1938 Harney Street, Suite 210, Laramie, Wyoming 82072, United States.ORCID https://orcid.org/0000-0002-1339-8260

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Nicolas A. Blouin · 2012 to 2026
$56.8M
Zebrafish Models of CNS Injury and Locomotor RecoveryP20GM121310 · NIGMS · UNIVERSITY OF WYOMING · PI Brandon L Roberts · 2017 to 2026
$27.2M
Coordinating Unit for DiaCompU24DK115255 · NIDDK · AUGUSTA UNIVERSITY · PI MCINDOE, RICHARD A. · 2017 to 2020
$11.6M
Development of a New Treatment for Diabetic WoundsR41DK125213 · NIDDK · NUTRIWYO, LLC · PI NAIR, SREEJAYAN · 2020 to 2020
$241k
NIDDK NIH HHS R41 DK125213NIDDK NIH HHS U24 DK115255NIGMS NIH HHS P20 GM103432NIGMS NIH HHS P20 GM121310
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cathepsin Kdiabetesmouse modelodanacatibporcine modelwound healing

Identifiers

PMID40799384
PMCPMC12338955

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.