Evidence map›Paper›PMID 40799520›Full record

SynthesisFrontiers in nutrition2025

Predictive value of geriatric nutritional risk index in patients with pancreatic cancer: a meta-analysis.

Yaqi Hua, Yi Yuan, Chen Zhou, Liping Liu, Yan Hu, Ping Tu, Dongying Li

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaqi HuaDepartment of Intensive Care Unit, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Yi YuanSchool of Nursing, University of South China, Hengyang, Hunan, China.
Chen ZhouDepartment of Intensive Care Unit, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Liping LiuNursing Department, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Yan HuWound Ostomy Clinic, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Ping TuDepartment of Post Anesthesia Care Unit, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Dongying LiDepartment of Intensive Care Unit, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: While growing evidence supports the Geriatric Nutritional Risk Index (GNRI) as a prognostic indicator for various cancers, its predictive value in pancreatic cancer remains unclear. This meta-analysis systematically evaluates GNRI's ability to predict postoperative complications and long-term outcomes in pancreatic cancer patients. Methods: We conducted a comprehensive literature search across nine databases (Web of Science, PubMed, Embase, Cochrane Library, Scopus, WanFang, CNKI, VIP, and SinoMed) through June 1, 2025. Hazard ratios (HRs) with 95% confidence intervals (CIs) were used to assess overall survival (OS), while risk ratios (RRs) with 95% CIs evaluated postoperative complications. Results: From 233 initially identified studies, 10 met inclusion criteria (n = 2,003 patients). Pooled analysis revealed that lower GNRI significantly predicted worse OS (HR = 1.92, 95% CI 1.54-2.41, Conclusion: GNRI shows promise as a clinically useful predictor of OS and POPF in pancreatic cancer patients. However, these findings require validation through prospective multicenter studies. Systematic review registration: Identifier CRD42023409362.

Indexed as

geriatric nutritional risk indexmeta-analysispancreatic cancerprognosissurvival

Identifiers

PMID40799520
PMCPMC12341475

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.