Evidence map›Paper›PMID 40799585›Full record

ArticlebioRxiv : the preprint server for biology2025

Depletion of a neural cell adhesion molecule disrupts both epithelial and germ layer identity in sea anemone embryos.

Anna Postnikova, Julissa Tello, Maristhela Alvarez, Grace Lee, Ilhan Ali, Christine M Field, Timothy J Mitchison, Katerina Ragkousi

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna PostnikovaDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Julissa TelloDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Maristhela AlvarezDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Grace LeeDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Ilhan AliDepartment of Biology, Amherst College, Amherst, MA 01002, USA.
Christine M FieldDepartment of Systems Biology, Harvard Medical School, Boston, MA, USA.
Timothy J MitchisonDepartment of Systems Biology, Harvard Medical School, Boston, MA, USA.
Katerina RagkousiDepartment of Biology, Amherst College, Amherst, MA 01002, USA.ORCID 0000-0001-9383-225X

Funding

Cell cycle regulation of polarity proteins in proliferating epitheliaR15GM141979 · NIGMS · AMHERST COLLEGE · PI RAGKOUSI, KATERINA · 2021 to 2023
$553k
NIGMS NIH HHS R15 GM141979
6 · The paper itself

Abstract

Assembly of cells into epithelial layers marks the early steps of tissue organization and embryonic development in most animals. Although several conserved proteins are known to be essential for epithelialization in bilaterians, it is unclear whether these are sufficient to drive epithelial organization in all metazoans. Using proteomics and knockdown approaches in embryos of the early-branching sea anemone

Identifiers

PMID40799585
PMCPMC12340817

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.