Evidence map›Paper›PMID 40800753›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2025

Spurious correlations in surface-based functional brain imaging.

Jayson Jeganathan, Nikitas C Koussis, Bryan Paton, Richa Phogat, James Pang, Sina Mansour L, Andrew Zalesky, Michael Breakspear

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Geometric influences on the regional organization of the mammalian brain.bioRxiv : the preprint server for biology · 2025
    Article
  5. The effect of spherical projection on spin tests for brain maps.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jayson JeganathanSchool of Psychological Sciences, College of Engineering, Science and the Environment, University of Newcastle, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0003-4175-918X
Nikitas C KoussisHunter Medical Research Institute, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0002-1097-3223
Bryan PatonSchool of Psychological Sciences, College of Engineering, Science and the Environment, University of Newcastle, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0001-6777-5001
Richa PhogatSchool of Psychological Sciences, College of Engineering, Science and the Environment, University of Newcastle, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0003-3340-9112
James PangSchool of Psychological Sciences, Turner Institute for Brain and Mental Health, and Monash Biomedical Imaging, Monash University, Victoria, Australia.ORCID https://orcid.org/0000-0002-2461-2760
Sina Mansour LCentre for Sleep & Cognition & Centre for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID https://orcid.org/0000-0002-5695-5696
Andrew ZaleskySystems Lab, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia.ORCID https://orcid.org/0000-0003-2298-9908
Michael BreakspearSchool of Psychological Sciences, College of Engineering, Science and the Environment, University of Newcastle, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0003-4943-3969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of functional MRI (fMRI) data is increasingly performed after mapping from volumetric voxels to surface vertices. Processing pipelines commonly used to achieve this mapping produce meshes with uneven vertex spacing, with closer neighbours in sulci compared to gyri. Consequently, correlations between the fMRI time series of neighbouring sulcal vertices are stronger than expected. However, the causes, extent, and impacts of this "gyral bias" are not completely understood or widely appreciated. We explain the origins of this bias, and using

Indexed as

biasfMRIparcellationsurface

Identifiers

PMID40800753
PMCPMC12319870

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.