Evidence map›Paper›PMID 40800985›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2025

An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain.

Sébastien Piluso, Csaba Verasztó, Harry Carey, Émilie Delattre, Thibaud L'Yvonnet, Éloïse Colnot, Armando Romani, Jan G Bjaalie, Henry Markram, Daniel Keller

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sébastien PilusoBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.ORCID https://orcid.org/0000-0002-4419-1748
Csaba VerasztóBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6295-7148
Harry CareyDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0002-4111-6259
Émilie DelattreBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.
Thibaud L'YvonnetBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.
Éloïse ColnotBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.
Armando RomaniBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6388-4286
Jan G BjaalieDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-7899-906X
Henry MarkramBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6164-2590
Daniel KellerBlue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Geneva, Switzerland.ORCID https://orcid.org/0000-0003-3280-6255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain atlases are indispensable tools for quantifying cellular composition across mouse brain regions. The widely used Common Coordinate Framework version 3 (CCFv3) from the Allen Institute delineates over 600 anatomical regions but lacks coverage of the most rostral and caudal brain areas, including the main olfactory bulb, cerebellum, and medulla. Additionally, the CCFv3 does not include annotations for key cerebellar layers, and its Nissl-stained reference volume is misaligned, limiting its efficiency. To overcome these limitations, we developed the Blue Brain Project (BBP) CCFv3 augmented atlas (CCFv3

Indexed as

atlasbraincentral nervous systemmouseregistration

Identifiers

PMID40800985
PMCPMC12319842

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.