ArticleTherapeutic advances in respiratory disease
Impact of exercise maintenance on mortality in interstitial lung disease: a population-based retrospective cohort study.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Incidence and risk factors for idiopathic pulmonary fibrosis in individuals aged 75 years and older in an ultra-aging society.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have proposed exercise capacity as a mortality predictor in individuals with interstitial lung disease (ILD). However, limited information is available regarding whether maintaining exercise is associated with improved survival in individuals with ILD.
objectivesWe aimed to evaluate the association between exercise maintenance and mortality in individuals with ILD using a longitudinal, large population-based database.
designThis retrospective cohort study used the Korean National Health Insurance claims-based database.
methodsWe analyzed a total of 3850 individuals with ILD who underwent two consecutive health screening examinations. The study exposure was the change in exercise habits between the two examinations, with individuals classified as exercisers (exercise maintainers and exercise non-maintainers) or non-exercisers. The primary outcome was mortality. We adjusted for age, sex, body mass index (BMI), smoking status, alcohol status, economic status, residential area, and comorbidities.
resultsDuring a median follow-up of 7.2 (interquartile range, 5.6-9.2) years, the incidence rate of death for exercisers was lower than that of non-exercisers (341.28 per 10,000 person-years (PY) vs 401.81 per 10,000 PY). Multivariable Cox regression analysis showed that the risk of mortality was substantially lower in exercisers compared to non-exercisers (adjusted hazard ratio (aHR): 0.82, 95% confidence interval (CI): 0.72-0.94). The risk of reduction for death was correlated with exercise adherence, with the lowest risk among exercise maintainers (aHR: 0.78 (0.66-0.92)) followed by exercise non-maintainers (aHR: 0.85 (0.73-0.99)), compared to non-exercisers. In subgroup analyses, BMI and economic status had a significant interaction in the association between exercise and mortality. The risk of death was lower in individuals with a lower BMI and higher economic status compared to their counterparts.
conclusionAmong individuals with ILD, the risk of death was inversely correlated with the level of exercise adherence, cautiously suggesting the importance of exercise maintenance in individuals with ILD.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.