Evidence map›Paper›PMID 40801083›Full record

ArticleACS chemical neuroscience2025

Fiber Photometry Analysis of Spontaneous Dopamine Signals: The

Conner W Wallace, Emily K DiMarco, Clare Y Slinkard, Rachael Shaughnessy, Katherine M Holleran, Samuel W Centanni, Christopher C Lapish, Sara R Jones

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Conner W WallaceDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID 0000-0002-7050-8761
Emily K DiMarcoDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID 0000-0003-2950-4395
Clare Y SlinkardDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Rachael ShaughnessyEastern Virginia Medical School, Old Dominion University, Norfolk, Virginia 23501, United States.
Katherine M HolleranDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID 0000-0002-2931-8157
Samuel W CentanniDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.
Christopher C LapishDepartment of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States.
Sara R JonesDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID 0000-0002-3424-7576

Funding

Wake Forest Translational Alcohol Research Center (WF-TARC)P50AA026117 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jeffrey L. Weiner · 2018 to 2026
$16.2M
MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1M
Role of Kappa Opioid Receptors in Maladaptive Catecholamine Responses to Stress and Alcohol ExposureU01AA014091 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Katherine Mercedes Holleran, SARA RAULERSON JONES · 2003 to 2026
$7.7M
Biased Kappa Opioid Agonists as Non-addictive AnalgesicsR01DA048490 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JONES, SARA RAULERSON, MARTIN, THOMAS JEFFREY · 2019 to 2023
$3.4M
Kappa Opioid Receptors and Phospho-Dopamine Transporters Drive Cocaine RewardR01DA054694 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI LANKUPALLE D JAYANTHI, SARA RAULERSON JONES · 2022 to 2026
$3.2M
The Neurobiology of Drug AbuseT32DA041349 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SARA RAULERSON JONES · 2017 to 2026
$1.8M
NIAAA NIH HHS P50 AA026117NIAAA NIH HHS T32 AA007565NIAAA NIH HHS U01 AA014091NIDA NIH HHS R01 DA048490NIDA NIH HHS R01 DA054694NIDA NIH HHS T32 DA041349
6 · The paper itself

Abstract

Fluorescent sensors have revolutionized the measurement of molecules in the brain, and the dLight dopamine sensor has been used extensively to examine reward- and cue-evoked dopamine release, but only recently has the field turned its attention to spontaneous release events. Analysis of spontaneous events typically requires evaluation of hundreds of events over minutes to hours, and the most common method of analysis,

Indexed as

DopamineNucleus AccumbensPhotometryAnimalsBenzazepinesCocaineDopamine AntagonistsDopamine Uptake InhibitorsMaleMiceMice, Inbred C57BLRacloprideBenzazepinesCocaineDopamineDopamine AntagonistsDopamine Uptake InhibitorsRacloprideSCH 23390analysis methodologydLightdopamine releasedopamine reuptakefiber photometryspontaneous signaling

Identifiers

PMID40801083
PMCPMC13245556

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.