Evidence map›Paper›PMID 40801546›Full record

ArticleMicrobiology spectrum2025

Leonardo Leal de Castro, Barbara Gomes da Rosa, Maria Carolina Peixoto-Rodrigues, Amanda Roberta Revoredo Vicentino, Vanderlei da Silva Fraga-Junior, Cynthia M Cascabulho, Luan Pereira Diniz, Claudia Farias Benjamim, Oliver Bracko, Julio Scharfstein and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Leonardo Leal de CastroLaboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Barbara Gomes da RosaLaboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Maria Carolina Peixoto-RodriguesLaboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Amanda Roberta Revoredo VicentinoLaboratório de Imunologia Molecular e Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Vanderlei da Silva Fraga-JuniorLaboratório de Imunologia Molecular e Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Cynthia M CascabulhoLaboratório de Inovações em Terapias, Ensino e Bioprodutos, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Luan Pereira DinizLaboratório de Investigação Metabólica Associada ao Envelhecimento, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Claudia Farias BenjamimLaboratório de Imunologia Molecular e Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Oliver BrackoDepartment of Biology, University of Miami, Miami, Florida, USA.
Julio ScharfsteinLaboratório de Imunologia Molecular e Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Daniel AdesseLaboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.ORCID 0000-0002-7421-9510

Funding

Neutrophil-driven vascular inflammation in VCID and Mixed Alzheimer's DiseaseR01NS141137 · UNIVERSITY OF MIAMI CORAL GABLES · 2025 to 2025
$604k
Conselho Nacional de Desenvolvimento Científico e Tecnológico 442178/2024-7Conselho Nacional de Desenvolvimento Científico e Tecnológico INCTS-INBEBFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de JaneiroFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010-001199/201Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.336/2021Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/202.024/2022(276047)Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/204.304/2025Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26-211.570/2019Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro SEI-26 260003/001351/2020Fundação Oswaldo Cruz Edital INOVA Geração de Conhecimento 2018 grant number 3231984391Fundação Oswaldo Cruz IOC-008-FIO-23Fundação Oswaldo Cruz IOC-026-FIO-21NIA NIH HHS R21 AG075798NIA NIH HHS R21 AG082193NINDS NIH HHS R01 NS141137
6 · The paper itself

Abstract

Toxoplasmosis is caused by infection with IMPORTANCE:

Indexed as

Chemokine CX3CL1MicrogliaNeuronsToxoplasmaToxoplasmosisAnimalsBlood-Brain BarrierCells, CulturedCerebral CortexMiceMice, Inbred C57BLSignal TransductionChemokine CX3CL1Cx3cl1 protein, mouseangiogenesisblood-brain barrierfractalkineneuroinflammationToxoplasma gondii

Identifiers

PMID40801546
PMCPMC12502563

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.