ReviewCells2025
Liver Regeneration as a Model for Studying Cellular Plasticity in Mammals: The Roles of Hepatocytes and Cholangiocytes.
Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Extracellular Matrix in Liver Regeneration: Biological and Therapeutic Insights.Bioengineering (Basel, Switzerland) · 2026Review
- Liver Innervation in Health and Disease: Neuroimmune-Neurovascular Interface and Future Therapeutic Implications.Biomedicines · 2025Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In most countries, liver disease is one of the most common pathologic conditions among the population. In this regard, the development of new methods to treat liver diseases is not possible without understanding the mechanisms of regeneration of this organ. A characteristic reaction of the liver to certain damaging factors is a pronounced cellular plasticity; this primarily concerns hepatocytes and cholangiocytes. This property is also characteristic of Ito stellate cells and macrophages. In this study, we focus on the plasticity of hepatocytes and cholangiocytes. We consider such manifestations of plasticity as the ability to enter the mitotic cycle, as well as transdifferentiation. The contribution of each type of plasticity to liver regeneration is considered, as well as the molecular mechanisms providing the cellular plasticity of hepatocytes and cholangiocytes.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.