Evidence mapPaperPMID 40801586Full record

ReviewCells2025

Rejuvenated Autologous Adult Stem Cells: Emerging Front Runners in the Fight Against Aging and Associated Diseases.

An Yu, Changguo Ma, Min Hu

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

An YuYunnan Key Laboratory of Cell Therapy for Refractory Diseases, Kunming University, Kunming 650214, China.
Changguo MaYunnan Key Laboratory of Cell Therapy for Refractory Diseases, Kunming University, Kunming 650214, China.
Min HuYunnan Key Laboratory of Cell Therapy for Refractory Diseases, Kunming University, Kunming 650214, China.

Funding

The Role of Immunoproteasome Function in Alzheimer's Disease and AgingR01AG070075 · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2025 to 2025
$721k
NIA NIH HHS R01 AG070075NIA NIH HHS RF1 AG070075Yunnan Fundamental Research Projects 202201AU070040Yunnan Provincial Department of Education 2025J0756
6 · The paper itself

Abstract

The growing global elderly population underscores the escalating importance of anti-aging interventions to combat age-related diseases and extend both health span and lifespan. Over the past decades, various anti-aging interventions have gained recognition, each with its unique set of advantages and limitations. Notably, the transplantation of rejuvenated autologous adult stem cells is standing out as a powerful strategy that holds significant promise in combating age-related functional decline and diseases. This review delves into our current biological insights into cellular rejuvenation and provides an overview of both pre-clinical and clinical experiences with autologous and allogeneic adult stem cell transplantations. It reinforces the concept that rejuvenated adult stem cells constitute a pivotal element in the quest for the fountain of youth. Additionally, we examine the technical challenges involved in obtaining and utilizing these rejuvenated adult stem cells.

Indexed as

Adult Stem CellsAgingRejuvenationAnimalsHumansStem Cell TransplantationTransplantation, Autologousadult stem cellsautologous transplantationcellular rejuvenationcellular reprogramming

Identifiers

PMID40801586
PMCPMC12346885

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.