Evidence map›Paper›PMID 40801625›Full record

ReviewCells2025

Lipid-lncRNA Crossroads: An Overview of Interactions Between Lipids and lncRNA.

Andrea Bayona-Hernandez, Ana Miladinović, Ludovica Antiga, Pavel Hozak, Martin Sztacho, Enrique Castano

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea Bayona-HernandezUnidad de Biologia Integrativa, Centro de Investigación Científica de Yucatán, A.C., Mérida 97205, Yucatan, Mexico.ORCID 0009-0003-1748-024X
Ana MiladinovićDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, 142 20 Prague, Czech Republic.ORCID 0009-0005-1824-1704
Ludovica AntigaDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, 142 20 Prague, Czech Republic.ORCID 0009-0003-7645-093X
Pavel HozakDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, 142 20 Prague, Czech Republic.ORCID 0000-0003-1901-1394
Martin SztachoLaboratory of Cancer Cell Architecture, Institute of Biochemistry and Experimental Oncology, First Faculty of Medicine, Charles University, 128 00 Prague, Czech Republic.ORCID 0000-0002-8496-1364
Enrique CastanoUnidad de Biologia Integrativa, Centro de Investigación Científica de Yucatán, A.C., Mérida 97205, Yucatan, Mexico.ORCID 0000-0003-2645-9541

Funding

Grant Agency of the Czech Republic 17-09103SInstitute of Molecular Genetics of the Czech Academy of Sciences RVO: 68378050Microscopy Centre - Light/Electron CF, IMG CAS supported by the MEYS CR project LM2023050 Czech-BioImagingPan-European Network in Lipidomics and EpiLipidomics CA19105 EpiLipidNETThe National Institute for Cancer Research NPO EXCELES, ID Project No. LX22NPO5102
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) interact with a variety of biomolecules, including DNA, mRNAs, microRNA, and proteins, to regulate various cellular processes. Recently, their interactions with lipids have gained increasing attention as an emerging research area. Both lipids and lncRNAs play central roles in cellular regulation, and growing evidence reveals a complex interplay between these molecules. These interactions contribute to key biological functions, such as cancer progression, lipid droplet transport, autophagy, liquid-liquid phase separation, and the formation of organelles without membranes. Understanding the lipid-lncRNA interface opens new avenues for unraveling cellular regulation and disease mechanisms, holding great potential not only for elucidating the fundamental aspects of cellular biology but also for identifying innovative therapeutic targets for metabolic disorders and cancer. This review highlights the biological relevance of lipid-lncRNA interactions by exploring their roles in cellular organization, regulation, and diseases, including metabolic and cancer-related disorders.

Indexed as

Lipid MetabolismLipidsRNA, Long NoncodingAnimalsHumansNeoplasmsLipidsRNA, Long NoncodinglncRNAphase separationphospholipids

Identifiers

PMID40801625
PMCPMC12346853

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.