Evidence map›Paper›PMID 40801807›Full record

ArticleeLife2025

Transcriptional dynamics uncover the role of BNIP3 in mitophagy during muscle remodeling in

Hiroki Taoka, Tadayoshi Murakawa, Kohei Kawaguchi, Michiko Koizumi, Tatsuya Kaminishi, Yuriko Sakamaki, Kaori Tanaka, Akihito Harada, Keiichi Inoue, Tomotake Kanki and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiroki Taoka *Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0008-1198-3790
Tadayoshi Murakawa *School of Life Science and Technology, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0003-1376-8772
Kohei KawaguchiCell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan.
Michiko KoizumiCell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan.
Tatsuya KaminishiDepartment of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan.ORCID https://orcid.org/0000-0001-5056-1074
Yuriko SakamakiOchanomizu Research Facility (ORF), Bioscience Center, Research Infrastructure Management Center, Institute of Science Tokyo, Tokyo, Japan.
Kaori TanakaDivision of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Akihito HaradaDivision of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Keiichi InoueDepartment of Cellular Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tomotake KankiDepartment of Cellular Physiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yasuyuki OhkawaDivision of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0001-6440-9954
Naonobu FujitaCell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-1914-8438

Funding

Japan Agency for Medical Research and Development 24gm6410016h0001Japan Science and Technology Agency 10.52926/JPMJPR18H8Japan Society for the Promotion of Science 21H05147Ministry of Education, Culture, Sports, Science, and Technology JPMXP1323015486
6 · The paper itself

Abstract

Differentiated muscle cells contain myofibrils and well-organized organelles, enabling powerful contractions. Muscle cell reorganization occurs in response to various physiological stimuli; however, the mechanisms behind this remodeling remain enigmatic due to the lack of a genetically trackable system. Previously, we reported that a subset of larval muscle cells is remodeled into adult abdominal muscle through an autophagy-dependent mechanism in

Indexed as

Drosophila melanogasterDrosophila ProteinsMembrane ProteinsMitochondrial ProteinsMitophagyTranscription, GeneticAnimalsAutophagy-Related ProteinsLarvaMitochondriaAtg8a protein, DrosophilaAutophagy-Related ProteinsDrosophila ProteinsMembrane ProteinsMitochondrial ProteinsautophagyBNIP3cell biologydevelopmental biologyD. melanogasterDrosophilametamorphosismitochondriamuscle

Identifiers

PMID40801807
PMCPMC12349898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.