Evidence map›Paper›PMID 40801835›Full record

ArticleAntimicrobial agents and chemotherapy2025

Thiazole substitution of a labile amide bond-a new option toward antiplasmodial pantothenamide-mimics.

Xiangning Liu, Annica Chu, Mina Nekouei, Chunling Blue Lan, Alexandre Pierret, Karine Auclair, Kevin J Saliba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. TheScience advances · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiangning LiuResearch School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.
Annica ChuDepartment of Chemistry, McGill University, Montreal, Québec, Canada.
Mina NekoueiDepartment of Chemistry, McGill University, Montreal, Québec, Canada.
Chunling Blue LanDepartment of Chemistry, McGill University, Montreal, Québec, Canada.
Alexandre PierretDepartment of Chemistry, McGill University, Montreal, Québec, Canada.
Karine AuclairDepartment of Chemistry, McGill University, Montreal, Québec, Canada.ORCID 0000-0003-0933-7956
Kevin J SalibaResearch School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.ORCID 0000-0003-3345-8440

Funding

Canadian Institute of Health Research PJT186220
6 · The paper itself

Abstract

The emergence and spread of artemisinin-partial resistant, malaria-causing

Indexed as

AmidesAntimalarialsPantothenic AcidPlasmodium falciparumThiazolesAminoacyltransferasesCoenzyme AHumansPhosphotransferases (Alcohol Group Acceptor)Protozoan ProteinsAmidesAminoacyltransferasesAntimalarialsCoenzyme Apantothenate kinasePantothenic AcidPhosphotransferases (Alcohol Group Acceptor)Protozoan ProteinsThiazolesantimalarial agentscoenzyme Adrug synthesisdrug targetsmalariaPlasmodium falciparum

Identifiers

PMID40801835
PMCPMC12406685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.