Evidence map›Paper›PMID 40802221›Full record

ArticleCardiovascular toxicology2025

Chronic Mercury Exposure Triggers Vascular Remodeling and Impaired Vasoconstriction in Small Intrapulmonary Arteries.

Ingridy Reinholz Grafites Schereider, Lorraine Christiny Costa Sepulchro Mulher, Nina Bruna de Souza Mawandji, Vanessa Cristina de Oliveira Souza, Fernando Barbosa Junior, Júlia Martins Vieira, Maylla Ronacher Simões, Dalton Valentim Vassallo

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ingridy Reinholz Grafites SchereiderDepartamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468, Vitória, ES, 29040-091, Brazil. ingridy_grafit@hotmail.com.ORCID 0000-0002-6379-4050
Lorraine Christiny Costa Sepulchro MulherDepartamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468, Vitória, ES, 29040-091, Brazil.
Nina Bruna de Souza MawandjiDepartamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468, Vitória, ES, 29040-091, Brazil.
Vanessa Cristina de Oliveira SouzaFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo - USP, Ribeirão Preto, SP, Brazil.
Fernando Barbosa JuniorFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo - USP, Ribeirão Preto, SP, Brazil.
Júlia Martins VieiraDepartamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468, Vitória, ES, 29040-091, Brazil.
Maylla Ronacher SimõesDepartamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468, Vitória, ES, 29040-091, Brazil.
Dalton Valentim VassalloDepartamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468, Vitória, ES, 29040-091, Brazil.

Funding

Fundação de Amparo à Pesquisa e Inovação do Espírito Santo 06/2017
6 · The paper itself

Abstract

Mercury exposure is a significant environmental concern due to its toxic effects on the human body, especially on the cardiovascular system. Its accumulation induces oxidative stress, inflammation and endothelial dysfunction in systemic arteries, contributing to the development of cardiovascular diseases. The close relationship between systemic and pulmonary circulation leads us to believe that it must also suffer by the toxic effects of HgCl

Indexed as

Mercuric ChloridePulmonary ArteryVascular RemodelingVasoconstrictionAnimalsHydrogen PeroxideMaleNitric OxideOxidative StressRatsRats, Sprague-DawleyHydrogen PeroxideMercuric ChlorideNitric OxideEndothelial dysfunctionIntrapulmonary arteryMercuryOxidative stressVascular reactivity

Identifiers

PMID40802221

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.