Evidence map›Paper›PMID 40802416›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2025

Relationship between vascular endothelial growth factor gene polymorphisms and Crimean-Congo hemorrhagic fever.

Umut Safiye Şay Coşkun, Serbülent Yiğit, Recai Aci, Ercan Tural, Nihan Bozkurt, Hüseyin Şener Barut

Abstract read
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In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Umut Safiye Şay CoşkunTokat Gaziosmanpaşa University, Faculty of Medicine, Department of Medical Microbiology - Tokat, Türkiye.ORCID http://orcid.org/0000-0002-4359-4799
Serbülent YiğitOndokuz Mayıs University, Faculty of Veterinary Medicine, Department of Genetics - Samsun, Türkiye.ORCID http://orcid.org/0000-0002-1019-3964
Recai AciAydın Adnan Menderes University, Söke Vocational School of Health Services - Aydın, Türkiye.ORCID http://orcid.org/0000-0002-1517-3356
Ercan TuralOndokuz Mayıs University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Division of Physiotherapy and Rehabilitation - Samsun, Türkiye.ORCID http://orcid.org/0000-0003-3894-7761
Nihan BozkurtTokat Gaziosmanpaşa University, Faculty of Medicine, Department of Medical Biology - Tokat, Türkiye.ORCID http://orcid.org/0000-0002-2283-0828
Hüseyin Şener BarutMinistry of Health, Tepecik Training and Research Hospital, Department of Infectious Disease - İzmir, Türkiye.ORCID http://orcid.org/0000-0003-2047-8573

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to investigate the relationship between vascular endothelial growth factor gene polymorphisms and Crimean-Congo hemorrhagic fever.

methodsA total of 130 serum samples were analyzed, including 60 patients diagnosed with Crimean-Congo hemorrhagic fever and 70 healthy controls. Genetic analyses were performed using polymerase chain reaction and restriction fragment length polymorphism techniques.

resultsSignificant differences were observed between patient and control groups in terms of vascular endothelial growth factor -460 C/T and -ID (18 bp) polymorphisms.

conclusionVascular endothelial growth factor gene polymorphisms may contribute to genetic susceptibility to Crimean-Congo hemorrhagic fever. Further studies with larger sample sizes are recommended to support these findings.

Indexed as

Genetic Predisposition to DiseaseHemorrhagic Fever, CrimeanPolymorphism, GeneticVascular Endothelial Growth Factor AAdultCase-Control StudiesFemaleGene FrequencyGenotypeHumansMaleMiddle AgedPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthYoung AdultVascular Endothelial Growth Factor A

Identifiers

PMID40802416
PMCPMC12341422

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.