Evidence map›Paper›PMID 40803607›Full record

Trial reportDiabetes technology & therapeutics2025

Trends in Total Daily Dose and Variability of Insulin Requirements in Newly Diagnosed Children and Adolescents with Type 1 Diabetes over 48 Months.

Chloë Royston, Julia Ware, Janet M Allen, Malgorzata E Wilinska, Sara Hartnell, Ajay Thankamony, Tabitha Randell, Atrayee Ghatak, Rachel E J Besser, Daniela Elleri and 5 more

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Diabetes technology & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chloë RoystonInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.
Julia WareInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-4497-0979
Janet M AllenInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.
Malgorzata E WilinskaInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.
Sara HartnellWolfson Diabetes and Endocrine Clinic, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom.
Ajay ThankamonyDepartment of Paediatrics, University of Cambridge, Cambridge, United Kingdom.
Tabitha RandellDepartment of Paediatric Diabetes and Endocrinology, Nottingham Children's Hospital, Nottingham, United Kingdom.
Atrayee GhatakDepartment of Diabetes, Alder Hey Children's National Health Service Foundation Trust, Liverpool, United Kingdom.
Rachel E J BesserDepartment of Paediatrics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-4645-6324
Daniela ElleriDepartment of Diabetes, Royal Hospital for Sick Children, Edinburgh, United Kingdom.
Nicola TrevelyanPaediatric Diabetes, Southampton Children's Hospital, Southampton, United Kingdom.
Fiona M CampbellDepartment of Paediatric Diabetes, Leeds Children's Hospital, Leeds, United Kingdom.ORCID 0000-0002-7618-6759
Roman HovorkaInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.
Charlotte K BoughtonInstitute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-3272-9544
CLOuD Consortium

Funding

Department of Health 14/23/09
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1Hypoglycemic AgentsInsulinInsulin Infusion SystemsAdolescentBlood GlucoseChildFemaleHumansMaleBlood GlucoseHypoglycemic AgentsInsulinadolescentschildrencontinuous glucose monitorhybrid closed loopinsulin pumpinsulin variabilitynewly diagnosedtype 1 diabetes

Identifiers

PMID40803607
PMCPMC7618672

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.